The significant reduction in the outer nuclear layer and the loss of band signals in the photoreceptor layers in dogs with SARDS identified on OCT support the previous histopathology findings. Small detachments may occasionally be detected on OCT and they may leak fluorescein.
Purpose To determine whether bacteria are isolated from canine indolent ulcers and evaluate their influence on clinical outcomes. Methods Swabs for anaerobic and aerobic culture were collected from indolent ulcers of 43 client‐owned dogs presenting to the University of Saskatchewan Veterinary Medical Centre. Outcomes were compared between ulcers with bacterial isolates and those without. Medical therapy was reviewed. Results Bacteria were isolated in 8/43 ulcers: Three cultured two isolates and five cultured single isolates. Staphylococcus was the most common genus isolated and was present in six ulcers: Species included unspecified [2], pseudintermedius [2], schleiferi [1], and hominis [1]. Streptococcus was the second most common isolate present in two ulcers: Species included canis and agalactiae. Tobramycin was the most common antibiotic used in ulcers with bacterial isolates prior to referral (n = 3). One case did not have conclusive follow‐up data from the referring veterinarian and was therefore excluded from further analysis. All seven culture‐positive ulcers were recorded as healed without complication: six healing after one procedure and one healing after two procedures. Thirty‐five ulcers were culture‐negative. There was no difference in outcome between indolent ulcers with bacterial isolates and those with negative cultures (P = .7475). Conclusions Bacteria were isolated from 19% of indolent ulcers, and Staphylococcus was the most common isolate. Bacterial isolation did not influence outcome.
A novel case of a canine odontogenic parakeratinized cyst (COPC) that resulted in exophthalmos and palatine, maxillary, and zygomatic bone erosion in a 5-year-old Chihuahua dog is reported. Final diagnosis was aided by cross-sectional imaging (magnetic resonance imaging and computed tomography) and confirmed with histologic examination of the cyst wall.
Purpose To describe the complications of conjunctival graft surgery occurring in cases at a referral ophthalmic service and evaluate factors that lead to occurrence of complications in canine cases. Methods A retrospective case–control study was completed using data from the Veterinary Medical Center at the Western College of Veterinary Medicine, Saskatoon, Canada, between May 2015 and March 2020. Case records from dogs that underwent conjunctival pedicle graft surgery and subsequently either did or did not develop a conjunctival graft complication were reviewed. Results One hundred and six dogs undergoing conjunctival graft surgeries were identified. Sixteen conjunctival graft complications occurred, of which, eight led to negative outcomes. Univariable analysis comparing canine eyes that developed complications to control eyes revealed potential (p ≤ .05) differences between the groups in post‐operative fluoroquinolone use, Streptococcus canis isolation, intraoperative intravenous cefazolin use, corneal stromal white cell infiltrate, and mean ulcer diameter. The use of intraoperative cefazolin could not be effectively evaluated with available data; however, no dogs (n = 22) receiving intraoperative cefazolin developed complications. Multivariable analysis revealed that dogs that were treated with a second‐generation fluoroquinolone and that had S. canis isolated had higher odds of experiencing complications than dogs that were not treated with a second‐generation fluoroquinolone and that were S. canis negative (Odds ratio = 64.7 [95% CI 6.3–669], p < .0001). Conclusions Streptococcus species played a role in conjunctival graft complications in our study. Empiric selection of second‐generation fluoroquinolone monotherapy may need reconsideration given the frequent isolation of Streptococcus spp. from canine ulcers. The use of intraoperative cefazolin may be associated with a lower complication rate.
Purpose To compare the scanning laser ophthalmoscopy (SLO), optical coherence tomography (OCT), and fluorescein angiography (FA) findings in retrievers with a single unilateral circular retinal plaque to those of an English springer spaniel with bilateral retinal dysplasia. Procedures A retrospective record review identified three dogs with circular retinal plaques that underwent SLO and OCT; in two of the three dogs, FA was also completed. Morphologic changes, lesion measurements, and angiogram characteristics were documented. An English springer spaniel with bilateral retinal dysplasia that had undergone SLO, OCT, and FA was used for comparison. Results Scanning laser ophthalmoscopy of the retriever dogs revealed circular retinal plaques with a dark periphery located in the tapetal retina. OCT revealed a thickening of the nerve fiber layer corresponding to the circular pattern observed on SLO. Within the circular plaque, the retina was predominantly of normal architecture. FA revealed variable hypofluorescence of both the rim and the center of the circular lesion throughout the early angiogram phases. In the late recirculation phase, small multifocal areas of hyperfluorescence were observed. OCT of geographic retinal dysplasia in the English springer spaniel revealed disorganization of both inner and outer retinal layers, and retinal detachment. Conclusions Circular plaques observed in the tapetal retina are predominantly formed by a thickening of inner retina, while retinal dysplasia has disorganization of both inner and outer retinal layers. Further etiologic research is needed, including pedigree mapping to determine whether retinal plaques are an acquired or inherited condition.
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