Elevated plasma concentrations of triglyceride (TG) and cholesterol (chol) are well recognized in diabetes (Saudek and Eder 1979), and are of potential importance in the pathogenesis of atherosclerosis. We measured lipids and lipoproteins in insulin and non-insulin treated diabetic patients, and in non-diabetic controls. Results are corrected for differences in body weight, and also related to glycaemic control and insulin levels. Methods We studied 104 adult diabetic outpatients and 89 age and sex matched controls. Plasma lipids and lipoproteins were measured after a 12 hour fast (Lipid Research Clinics Program, 1974). In the diabetics fasting plasma glucose, HbA 1 C (column chromatography) and insulin (McCarroll 1971) were also measured. Differences in lipoproteins were adjusted for the effects of body weight by an analysis of co-variance. Correlation coefficients were calculated for associations between lipoproteins and plasma glucose, HbA,C and insulin. Sig-Table 1 Plasma lipid and lipoprotein levels in diabetics and controls
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