This paper focuses on a new method to classify and convert the lower-body features of young females into the rules of individualized elements that are necessary for pant pattern design. Approaches used to develop a customized apparel pattern and their advantages and disadvantages are discussed in the literature review. Subsequently, a new method to analyze lower-body features for the development of individualized pant patterns is presented. The main method involved is the classification of certain body features into grades that provided alternatives for different body shapes, and the use of elements that are needed for pattern-making but that are difficult to measure directly in a three-dimensional image to predict the girths, half-girths and the other key measurements of a body. Three sets of rules were derived from this method: (a) individualized rules on height to classify the height at a feature into different grades, which help to find the location of the feature based on the height of a body; (b) individualized rules on girth to sort the thickness/width ratio of different cross-sections into grades at different features, which predict the girth of a characteristic feature from the thickness and the width of a feature; and (c) individualized rules on the crotch to find the relationship between the length of the measuring line at the divided points and the thickness of a certain girth, which reveal the individuality of the crotch and benefit the development of an individualized pant pattern. The method presented has the potential to realize individuality in female pant design by converting lower-body features into grades and establishing relationships with personalized parameters. This method can reduce the complexity of customization in pattern design.

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Intervertebral disc degeneration (IDD) is a major cause of lower back pain. However, to date, the molecular mechanism of the IDD remains unclear. Gene expression profiles and clinical traits were downloaded from the Gene Expression Omnibus (GEO) database. Firstly, weighted gene coexpression network analysis (WGCNA) was used to screen IDD-related genes. Moreover, least absolute shrinkage and selection operator (LASSO) logistic regression and support vector machine (SVM) algorithms were used to identify characteristic genes. Furthermore, we further investigated the immune landscape by the Cell-type Identification By Estimating Relative Subsets Of RNA Transcripts (CIBERSORT) algorithm and the correlations between key characteristic genes and infiltrating immune cells. Finally, a competing endogenous RNA (ceRNA) network was established to show the regulatory mechanisms of characteristic genes. A total of 2458 genes were identified by WGCNA, and 48 of them were disordered. After overlapping the genes obtained by LASSO and SVM-RFE algorithms, genes including LINC01347, ASAP1-IT1, lnc-SEPT7L-1, B3GNT8, CHRNB3, CLEC4F, LOC102724000, SERINC2, and LOC102723649 were identified as characteristic genes of IDD. Moreover, differential analysis further identified ASAP1-IT1 and SERINC2 as key characteristic genes. Furthermore, we found that the expression of both ASAP1-IT1 and SERINC2 was related to the proportions of T cells gamma delta and Neutrophils. Finally, a ceRNA network was established to show the regulatory mechanisms of ASAP1-IT1 and SERINC2. In conclusion, the present study identified ASAP1-IT1 and SERINC2 as the key characteristic genes of IDD through integrative bioinformatic analyses, which may contribute to the diagnosis and treatment of IDD.

VX Sgr is a red supergiant at an adopted distance of 1.6 kpc with intense 43 GHz SiO maser emission. In this paper, we present the high-resolution very long baseline interferometry (VLBI) observations of SiO masers toward VX Sgr at five epochs. We used the Very Long Baseline Array to map the J = 1→0 (v = 1, 2) 28 SiO masers and confirmed a ring-like structure. In the first two epochs, the v = 1 masers form a ring, but v = 2 maser spots residing only in the southern and northern regions do not form a complete ring. In the third epoch, the two masers are distributed in a ring structure and the v = 2 masers are a bit closer to the central star. In the last two epochs, many new maser spots appear and overlap each other. These overlapping maser spots can be related to the shock waves and reflect the collisional pumping. We compare the observations with the pumping models and speculate that the real pumping mechanism may be complex in VX Sgr and vary with time. The J = 1→0 (v = 0) 29 SiO line emission is also detected, but is too weak to produce any VLBI map.