We present a comprehensive analysis of pre-seismic anomalies as computed from the ground and space-based techniques during the recent Samos earthquake in Greece on 30 October 2020, with a magnitude M = 6.9. We proceed with a multi-parametric approach where pre-seismic irregularities are investigated in the stratosphere, ionosphere, and magnetosphere. We use the convenient methods of acoustics and electromagnetic channels of the Lithosphere–Atmosphere–Ionosphere-Coupling (LAIC) mechanism by investigating the Atmospheric Gravity Wave (AGW), magnetic field, electron density, Total Electron Content (TEC), and the energetic particle precipitation in the inner radiation belt. We incorporate two ground-based IGS GPS stations DYNG (Greece) and IZMI (Turkey) for computing the TEC and observed a significant enhancement in daily TEC variation around one week before the earthquake. For the space-based observation, we use multiple parameters as recorded from Low Earth Orbit (LEO) satellites. For the AGW, we use the SABER/TIMED satellite data and compute the potential energy of stratospheric AGW by using the atmospheric temperature profile. It is found that the maximum potential energy of such AGW is observed around six days before the earthquake. Similar AGW is also observed by the method of wavelet analysis in the fluctuation in TEC values. We observe significant energetic particle precipitation in the inner radiation belt over the earthquake epicenter due to the conventional concept of an ionospheric-magnetospheric coupling mechanism by using an NOAA satellite. We first eliminate the particle count rate (CR) due to possible geomagnetic storms and South Atlantic Anomaly (SAA) by the proper choice of magnetic field B values. After the removal of the statistical background CRs, we observe a significant enhancement of CR four and ten days before the mainshock. We use Swarm satellite outcomes to check the magnetic field and electron density profile over a region of earthquake preparation. We observe a significant enhancement in electron density one day before the earthquake. The parameters studied here show an overall pre-seismic anomaly from a duration of ten days to one day before the earthquake.

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Atmospheric disturbances caused by seismic activity are a complex phenomenon. The Lithosphere–Atmosphere–Ionosphere Coupling (LAIC) (LAIC) mechanism gives a detailed idea to understand these processes to study the possible impacts of a forthcoming earthquake. The atmospheric gravity wave (AGW) is one of the most accurate parameters for explaining such LAIC process, where seismogenic disturbances can be explained in terms of atmospheric waves caused by temperature changes. The key goal of this work is to study the perturbation in the potential energy associated with stratospheric AGW prior to many large earthquakes. We select seven large earthquakes having Richter scale magnitudes greater than seven ( M > 7.0 ) in Japan (Tohoku and Kumamoto), Mexico (Chiapas), Nepal, and the Indian Ocean region, to study the intensification of AGW using the atmospheric temperature profile as recorded from the Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) satellite. We observe a significant enhancement in the potential energy of the AGW ranging from 2 to 22 days prior to different earthquakes. We examine the conditions of geomagnetic disturbances, typhoons, and thunderstorms during our study and eliminate the possible contamination due to these events.