Background: Despite the most significant efforts of many experts to provide natural therapeutic therapies, spinal cord injury (SCI) is a traumatic event with limited functional recovery. After a spinal cord injury, paraplegia can develop. Damage to the ligaments, vertebrae, or discs of the spinal column causes this. Paraplegia is the loss of muscle function in the lower half of the body, including both legs. Leg paralysis, in this case in which affects all parts of the pelvic organs, legs, and torso. This is partly owing to the complex character of SCI, which involves a great deal of disarray and malfunction as a result of the initial injury. Secondary degeneration is caused by neurotoxicity, vascular malfunction, neuroinflammation, apoptosis, and demyelination. Presentation of Case: 34year old male patient with wedge compression was diagnosed on x-ray after a fall from the tree. Discussion: The requirements for regeneration, rehabilitation, and neuroprotection appear to necessitate a diverse set of therapeutic approaches that can be used at different stages of the post-injury response. Conclusion: We'll focus on one strategy, in particular, physical training/exercise, which looks to have a wide range of applications and benefits for those with a chronic or acute SCI.

Coronavirus disease 2019 (COVID-19) has spread around the globe. The most common symptoms associated with this are usually respiratory, but different central nervous system manifestations have been reported. There are many cases of Guillain-Barre syndrome (GBS) post-COVID-19. However, only a few simultaneous afflictions of COVID-19 with GBS have been reported. Therefore, our study aims to investigate a case of GBS along with COVID-19 infection in India. A 22-year-old male with no medical history presented with fever along with global weakness and breathing difficulty. There was no history of travel. At the time of admission, he had developed quadriparesis and had muscular strength of 2/5 in bilateral lower limbs and 3/5 in bilateral upper limbs. When the patient developed breathing difficulty, he was transferred to the intensive care unit. The cerebrospinal fluid evaluation showed albumin-cytological dissociation, and a nerve conduction study was done. The patient was managed by neuro physiotherapy 34 days after COVID-19 exposure. After proper physiotherapy and rehabilitation, the patient was able to return to his college life.

Aim Oral malodor is a common condition caused by some Gram‐negative oral bacteria, among which are the 3 red complex bacteria (RCB). The present study investigated the effectiveness of the Ultrasound Tongue Scraper (UTS) to disrupt the structural morphology of the bacteria and their biofilm. Methods While developing over 72 hours, multispecies biofilms of RCB (Porphromonas gingivalis, Tryponema denticola, Tannerella forsythia) were treated every 24 hours with 1.6‐MHz ultrasound waves generated with UTS. An untreated group served as controls. Confocal laser scanning microscopy was used to determine the biofilm thickness, biomass and live : dead cell ratio at each time point (24, 48 and 72 hours). Biofilm morphology and bacteria ultrastructure were viewed using scanning/transmission electron microscopy, respectively. Data were analyzed using ANOVA and Tukey tests. Results At each time point, the 3 variables were significantly lower in treated samples than the untreated. Significant biofilm disruption was observed in treated samples at each time period while the untreated had intact biofilm morphology. Cells in treated samples showed disrupted cell wall, cytoplasmic material, huge vacuoles and heterogeneity in electron density, while these cell organelles remained intact in untreated samples. Conclusion The UTS has an inhibitory effect on RCB and could be useful for oral malodor management.

Stroke is among the world's leading causes of death, disability and functional inability for adults. The incidence of stroke currently exceeds that of Western developed nations in India. Increased understanding of the risk factors for stroke is hoped to lessen the future prevalence. Recurrence rates of stroke are high. The incidence and ability of individuals to recover varies widely. Stroke affects health by affecting the functioning system resulting in disabilities, physical problems, and a lower quality of life. Physiotherapy is instrumental to restore lost sensations and motor skills and to deal with patient's emotional needs. This case report describes a case of A 66 year old male retired PWD worker, who was referred to physiotherapy with complaints of weakness in left upper and lower extremities and inability to perform movements of left side. He had a sudden loss of power in the left side one day prior and was diagnosed with stroke along straightening of the dorso-lumbar spine and disc bulges at C2-C6, L4-S1 levels on X-ray and MRI scan. Physiotherapy rehabilitation was started with bed mobility and transfer activities with further progress to sitting and standing activity. As the transfers improved, we progressed to balance training, lower limb strengthening, and gait training in which task specific training was focused. Later, we concluded that balance and locomotor training has a great impact on functional recovery post-stroke.