Free radical is a reactive component because it has one or more electrons. Free radical is very dangerous for our body because it can cause degenerative diseases, such as cancer, heart attack, and aging. Cancer and heart attack are one of the most killer disease. All we can do to decrease the free radical effect is consume antioxidant. S. caseolaris leaves has antioxidant activity, but it has known yet which stage of maturity is the best one for produce the highest antioxidant activity. This purpose of this research is knowing the influence between maturity and antioxidant activity at different maturity stages. This method of this research is experimental with Completely Randomized Design. The treatment in this research is vitamin C, fresh leaves in ethanol 96% extract, young leaves in ethanol 96% extract, and mature leaves in ethanol 96% extract. The main parameter of this research is IC50 values and the secondary parameters are total content of phytochemical in every extract. Data analysis using descriptive method with 4 treatments and five replications. The result of this research show that the maturity has influence in antioxidant activity. Inhibitory concentration 50 (IC50) values of shoot leaves extract, young leaves extract and mature leaves extract is 12.0013 ppm, 13.9915 ppm and 14.6613 ppm. All of them are called antioxidant which has very strong activities. The highest phytochemical compound is found on shoot leaves extract with ethanol 96% solvent.

One of fishery products in Indonesia, namely shrimp. There are many products derived shrimp, there are frozen, fresh or shrimp species. Talk about International trade Indonesia one of which is exports, shrimp becomes a commodity which dominate the fishery exports, with the value of the donated amount of US $ 1.280 million, followed by tuna US $ 606 million, other fish US $ 700 million and fishery products other US $ 746 million. Exports of shrimp is the largest export value in penyumbangannya basis. Shrimp exports alone expanded to various countries in the world. The shrimp itself is set for Indonesia's main export commodity. PT. Grahamakmur Ciptapratama is one of the cold storage company exporters of shrimp that were in Sidoarjo, East Java. To maintain the quality of shrimp for export, certainly requires appropriate processes and technologies that support. It is also necessary human resources able to handle and process the shrimp according to the procedures applied. Based on the description above, the writer interested to know and assess the process of shrimp processing activities were noticed Critical Control Points (CCP). In the production process Frozen Vannamei Shrimp (Litopenaeus vannamei) in PT. Grahamakmur Ciptapratama, Sidoarjo - East Java, part of the raw material receiving, cooking, and a metal detector is a Critical Control Points (CCP), which needs to be maintained and monitored. The need for control of the CCP aims for the creation of food safety for consumers.