Fructose or often called fruit sugar is one part of simple carbohydrates calledmonosaccharides (Almatsir 2009). Currently, many food and beverage industries usefructose sugar as a sweetener. (Prahstuti 2011). Consumption of high-fructose productsof more than 85 grams per day or more than 25% of caloric needs can lead to increasedtriglyceride levels and insulin resistance (Prahastuti 2011). The purpose of this study wasto evaluate changes in obesity status, fasting blood glucose levels and triglyceride levelsin wistar rats induced with a high fat fructose diet, by giving different doses. Research methods.The design in this study was a Randomized Control Trial(RCT), double bline pre post control design using male wistar rats, aged 6-7 weeksweighing 90-150 grams, totaling 15 individuals divided into 3 groups. Group 1 is a groupof rats fed HFFD with 1% fructose, group 2 is rats fed HFFD with 2% fructose, group 3is rats fed standard feed. Before the treatment, adaptation was carried out for 1 week, afterthat a pre-test was carried out which included measurements of body weight, body length,fasting data glucose levels, and triglyceride levels. The treatment was given for 60 days,in the middle the measurements of body weight, length, fasting data glucose levels, andtriglyceride levels were also carried out. The research location was in the clinicalpathology laboratory, Faculty of Pharmacy, Muhammadiyah University, Surakarta. The results of the study The administration of fructose at a dose of 2% / kg BWincreased fasting blood glucose and triglyceride levels higher than the administration of1%. kgBB. Upgrade has started since day 30 Keywords: Fructose dose, Body Mass Index, fasting blood glucose level, Triglyceride level,Wistar rats, induced High fat fructose diet

A decrease in the hormone estrogen in women can trigger changes in nutritional status and cholesterol levels that cause hypercholesterolemia, so that antioxidant compounds and fiber are needed to improve one of them is in tempeh flour and rice bran. This study aims to prove the effect ofgiving a combination of tempeh flour and bran (Petul) on nutritional status and total cholesterol levels in menopausal women with hypercholesterolemia. Methods: Randomized control group pretest posttestcontrol group design, carried out on 60 menopausal women at least 1 year with hypercholesterolemia, not taking medication who were divided into intervention groups (given a formula 37.33 g / drink 3 times a day for 3 weeks) and placebo in the control group. The variables studied before and after the intervention were nutritional status and total cholesterol levels.Independent statistical analysis of t test, dependent t test and Ring spearmen correlation test. Results: Combination of PETUL as much as 37.33 g / drink 3 times / day for 3 weeks can improve nutritional status but has no significant and significant effect on reducing total cholesterol levels. Consclusion : PETUL formula can improve nutritional status and reduce total cholesterol levels.Keywords: Formula, Petul, nutritional status, menopausal women, hypercholesterolemia

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This study aims to determine the relationship between the percentage of body fat, fiber intake and hip waist circumference ratio with blood pressure of elderly. This type of research used an analytic observational study with a cross sectional approach. It was conducted on 46 elderly people selected by purposive sampling method. The data collected includes blood pressure, measurements using a sphygmomanometer. Measurement of body fat percentage using the BIA instrument. Measurement of fiber intake with a 2x24 hour food recall instrument. As well as measuring the ratio of waist to hip circumference with metline instruments. Testing the relationship between variables was analyzed using the chi-square test. The result 52.2% of the sample had a higher percentage of body fat. 60.9% of the sample had less fiber intake. 58.7% of the sample had a higher waist to hip ratio. 52.2% of the sample had hypertension I. There was a relationship between the percent of body fat (pvalue0.001), fiberintake (p value 0.001), and ratio of waist to hip circumference (p value 0.001) with blood pressure. Penelitian ini bertujuan untuk mengetahui hubungan antara persentase lemak tubuh, asupan serat, dan rasio lingkar pinggang pinggul (RLPP) dengan tekanan darah lansia. Jenis penelitian ini menggunakan studi observasional analitik dengan pendekatan cross sectional, dilakukan terhadap 46 orang lanjut usia dengan purposive sampling. Pengukuran persentase lemak tubuh dengan instrumen BIA. Pengukuran asupan serat dengan instrumen food recall 2x24 jam, RLPP dengan instrumen metline, tekanan darah dengan sphygmomanometer. Uji hubungan yang digunakan adalah uji chi-square. Hasil penelitian menunjukkan bahwa 52,2% sampel memiliki persen lemak tubuh yang lebih. Rerata persen lemak tubuh laki-laki dan perempuan adalah 20,20% dan 25,29%. Sebanyak 60,9% sampel memiliki asupan serat yang kurang. Rerata asupan serat sebesar 22,59 gram per hari. 58,7% sampel memiliki rasio lingkar pinggang pinggul yang lebih. Rerata RLPP laki-laki dan perempuan adalah 0,92 dan 0.84. 52,2% sampel mengalami hipertensiI. Rerata tekanan darah sebesar 158/98 mmHg. Terdapat hubungan antara persentase lemak tubuh (p value = 0,000), asupan serat (p value = 0,000), dan rasio lingkar pinggang pinggul (p value =0,000) dengan tekanan darah.

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