The study was carried out during a period of February 2017-July 2018 for the detection of brucellosis in 128 suspected patients with age group range from 17-69 years, who attended to Baghdad teaching hospitals, that had been examined and defined as suspected cases by specialized physician with the recording of clinical manifestation. The diagnosis done by Rose Bengal test (RBT) method, a blood sample was taken from each patients as well as other 30 healthy control matching in age and gender. The study included measurement of the concentration of Interleukin-23, activity of Acidphosphatase, Copper and Zinc in sera of patients and healthy control. The result indicated that Rose Bengal test positive in 18 cases, 12 with a titer of 1:160 and 6 cases with a titer of 1:320. The Level of IL-23, Acid phosphatase increased significantly, with no statistical difference in copper and zinc concentration in both interval ages of patients sera in comparison with healthy control.

Salmonella typhoid and paratyphoid are transmitted mainly by the fecal-oral route. This study was designed to find the correlation between Salmonella and IgM, IgG, and the levels of interleukin-33, TNF-α, and LTB 4. The study was carried out from March 2020 to January 2021 for the detection of Salmonellosis in 100 suspected patients with age group ranging from 17 - 69 years, who attended Baghdad teaching hospitals that had been examined and defined as suspected cases by a specialized physician with the recording of clinical manifestation. The diagnosis was done by immunochromatography method, a blood sample was taken from the patient as well as other 30 healthy controls matching in age and gender. The study included measurement of the level of interleukin -33, Tumor necrosis Factor α, and Leukotreins B4 level in sera of patients and healthy control. The results indicated that anti –salmonella IgM positive in 54 cases, anti- salmonella IgG positive in 46 cases, and 18 positive cases with both IgM and IgG.  The Level of interleukin 33, Tumor necrosis Factor – α increased significantly while the serum Leukotreins B4 level decreased significantly in patients sera as compared with healthy control.