Background: A ventilated middle ear space is an essential component of a functioning middle ear transformer mechanism. A mastoid ventilation tube (MVT) placed post-aurally in the antrum near the aditus is used in this study for the benefit of improvement in results of tympanoplasty. In support of this concept, very few experimental documents are reported. Aims and Objectives: The aims of this study were to find out if the MVT has any effect on the outcome of tympanoplasty in cases of chronic suppurative otitis media (CSOM) tubo-tympanic disease. Materials and Methods: This study was performed in 50 cases which were selected from the total number of cases using stratified random sampling method. In the research, patients with CSOM, who did not respond to medical therapy and required a combined approach tympanoplasty, were enrolled. Patients who needed just myringoplasty and those found to have cholesteatoma intraoperatively were not included in the research. Results: The study showed significant improvement in graft uptake, air-bone closure, and hearing in cases with MVT, thus resulting in better success rate in cases with MVT than cases without MVT. Furthermore, most of the cases had sclerosed mastoids and very few cases had complications such as MVT block and post-operative discharge. Conclusion: The MVT had a beneficial effect on the final outcome of combined approach tympanoplasty in cases of CSOM tubo-tympanic type active stage.

Background: The addition of Magnesium sulphate (MgSO4) to postoperative Fentanyl Epidural infusions has been demonstrated to reduce the requirement for Fentanyl. Methodology: Group I (38 patients) got Epidural Fentanyl 50 mg (1 cc) diluted and made up to 6 cc with normal saline, whereas Group II (38 patients) received Epidural Fentanyl 50 μg (1 cc) + MgSO4 50 mg (4 units in insulin syringe of 50% solution) diluted and made up to 6 cc with normal saline. The effects of analgesia on pulse rate and blood pressure were measured as well as the duration of analgesia. Results: In this study, an average age of the study population was 41.25 ± 3.25 years in Group I and 42.14 ± 4.42 years in Group II. The pulse rate in Group-I increased significantly from 105 minutes compared to Group-II, whereas it remained steady in Group-II throughout the research duration. Systolic BP increased significantly in Group-I after 90 minutes compared to Group-II, but remained steady in Group-II. SPO2 and respiratory rates did not differ significantly.Conclusion: Adding magnesium sulphate to fentanyl in epidural analgesia increased the duration of analgesia while maintaining hemodynamic stability.