Aims1) To determine the pooled prevalence of overweight and obesity in people with severe mental illness (SMI), overall and by type of SMI, geographical region, and year of data collection; and 2) to assess the likelihood of overweight and obesity, in people with SMI compared with the general population.MethodsPubMed, Medline, EMBASE, and PsycINFO databases were searched to identify observational studies assessing the prevalence of obesity in adults with SMI. Screening, data extraction and risk of bias assessments were performed independently by two co-authors. Random effect estimates for the pooled prevalence of overweight and obesity and the pooled odds of obesity in people with SMI compared with the general population were calculated. Subgroup analyses were conducted for types of SMI, setting, antipsychotic medication, region of the world, country income classification, date of data collection and sex. We assessed publication bias and performed a series of sensitivity analyses, excluding studies with high risk of bias, with low sample size and those not reporting obesity according to WHO classification.Result120 studies from 43 countries were included, the majority were from high income countries. The pooled prevalence of obesity in people with SMI was 25.9% (95% C.I. = 23.3-29.1) and the combined pooled prevalence of overweight and obesity was 60.1% (95% C.I. = 55.8-63.1). Sub-Saharan Africa (13.0%, 95%C.I. = 6.7-25.1) and South Asia (17.7%, 95%C.I. = 10.5-28.5) had the lowest prevalence of obesity whilst North Africa and the Middle East (35.8%, 95%C.I. = 23.8-44.8) reported the highest prevalence. People with SMI were 3.04 more likely (95% C.I. = 2.42-3.82) to have obesity than the general population, but there was no difference in the prevalence of overweight. Women with schizophrenia were 1.44 (95% C.I. = 1.25-1.67) times more likely than men with schizophrenia to live with obesity; however, no gender differences were found among those with bipolar disorder.ConclusionPeople with SMI have a markedly high prevalence and higher odds of obesity than the general population. This may contribute to the very high prevalence of physical health conditions and mortality in this group. People with SMI around the world would likely benefit from interventions to reduce and prevent obesity.

Salivary HGF levels positively correlated with PD progression and smoking status. A significant reduction in HGF levels was seen after NSPT. Thus, within limits, it can be suggested that HGF plays a role in PD progression and can be used as a diagnostic biomarker to detect disease activity. Salivary HGF levels could also be useful to monitor response to periodontal therapy.

Plasma cell gingivitis (PCG) is a condition in which a hypersensitive reaction is seen to various etiologic causes in the gingival tissue. A rare form of PCG, called plasma cell granuloma may sometimes occur, in which enlargement of a specific area of the mouth is seen. This case report elicits a case of such a rare case of the granuloma in the anterior maxilla of a 25-year-old patient.

The interest in evaluating therapeutic effects of plants has increased dramatically with more and more people inclining toward alternative medicine for their health care needs as they are effective, nontoxic, economical and usually have no sideeffects. Pomegranate is one such fruit/ plant which is beneficial with added effect on oral health.This plant source of polyphenols has antioxidant properties, meaning they help protect cells from damage and may lower the inflammation in the body. Apart from this various other components of the pomegranate plant such as flowers are rich source flavonoids. Peel extracts have been demonstrated to have antibacterial and antifungal activity due to the presence of hydrolysable tannins and polyphenols. The stem part is known to have astringent and antihelminthic properties and the leaves have been used for conjunctivitis.Thus, the purpose of this review is to summarize the therapeutic benefits of various extracts derived from the pomegranate plant and its benefits on oral health.

Context: Non-communicable diseases (cardiovascular diseases, hypertension, and diabetes) and comorbid common mental disorders are of public health concern because of their high morbidity and mortality rates. The authors undertook a systematic review of studies that reported the prevalence of common mental disorders among non-communicable diseases, specifically in India. Evidence acquisition: Relevant databases (Medline, Google Scholar, EBSCO, and ProQuest) were searched until May 2021. Descriptive and observation studies from the mentioned databases were included. Evidence synthesis: Of the total 6,515 studies, the electronic literature search identified 4,307 studies. Manual cross-referencing identified an additional 2,208 studies. Only 17 studies met the criteria and were included for the review. Findings: Twelves studies focused on the prevalence of anxiety and depression in patients with diabetes, three studies focused on cardiovascular disease, two on non-communicable diseases, and one on the prevalence of depression in hypertension. The range of the prevalence of anxiety disorder and depression was 3.9–44% and 8–44%, respectively. Conclusion: High prevalence of anxiety and depression is seen in people with diabetes, indicating these are of serious public health concerns in India.