This article presents new composite materials with cross-linked structures based on grafted copolymers of collagen with acrylates, which were prepared under photocatalytic conditions using the complex oxide RbTe1.5W0.5O6 and additional modifiers. Cross-linking agents for acrylate fragments were used. Triethylene glycol dimethacrylate (TEDMA) was used in small volumes, and acrylic acid (AA) was used in an amount similar to the MMA concentration. The properties of the obtained graft copolymers were studied. Thus, collagen containing acrylate graft copolymers with cross-linked structures, which are highly soluble in water, was obtained. Addition of the protein substrate modifier (polyethylene glycol (PEG)) in an amount comparable to collagen resulted in a coagulate with a cross-linked structure. The gel easily released water during drying in vacuum and formed a polymer composite film. According to the results, the new polymer materials which were obtained were fungi-resistant. Due to observed properties, the obtained polymer samples could be considered as new materials for medical products, including colloidal solutions, gels, films.