For an anesthesiologist, it is important to manage the hemodynamics of patients who develop atrial fibrillation (AF) during the perioperative period. In a patient undergoing Whipple surgery, atrial fibrillation, which is thought to occur with an astonishing intraoperative cause has not been reported in the literature. There are multiple risk factors for the development of new onset AF such as older age, diabetes, hypertension, hypovolemia, electrolyte imbalances, hypoxia, and underlying heart disease, etc. But also, during surgery, direct irritation of diaphragmatic surface of the heart with retractor may trigger AF.
Background: The aim of this study was to investigate the effects on QT interval of the propofol-ketamine combination and the midazolam-fentanyl combination in anesthesia induction for cardiac surgery. Methods: Between September 2020 and June 2021, a total of 9 5 c ardiac s urgery p atients ( 80 m ales, 1 5 f emales; mean age: 57±9.1 years; range, 26 to 76 years) were included. The patients were divided into two groups as Group PK (propofol-ketamine, n=50) and Group MF (midazolam-fentanyl, n=45). The 12-lead electrocardiographic and hemodynamic measurements were performed at three time points: before anesthesia induction, after anesthesia induction, and after endotracheal intubation. The measurements were evaluated with conventional Bazett's formula and a new model called index of cardio-electrophysiological balance. Results: The evaluated QTc values of 95 patients after anesthesia induction were significantly prolonged with the Bazett's formula and the index of cardio-electrophysiological balance in Group PK (p=0.034 and p=0.003, respectively). A statistically significant QTc prolongation was observed with the index of cardio-electrophysiological balance after laryngoscopy and endotracheal intubation in Group PK (p=0.042). Hemodynamic parameters were also higher in Group PK. Conclusion: Our study shows that the propofol-ketamine combination prolongs the QTc value determined by the Bazett's formula and the index of cardio-electrophysiological balance model. Using both QTc measurement models, the midazolam-fentanyl combination has no prolongation effect on QTc interval in coronary surgery patients.
Açık kalp cerrahisinde kanama nedenli reoperasyon mortalite ve morbiditeyi arttıran ciddi bir risk faktörüdür. Bu çalışmadaki amacımız, kanama nedeni ile reoperasyona alınan hastalarda, cerrahi ve koagülopati kanaması için olabilecek preoperatif ve intraoperatif risk faktörlerini araştırmaktır. Gereç ve Yöntem: Hastaların verileri, hastane elektronik sisteminden ve hastaların dosyalarından elde edildi. Kalp yetmezliği ameliyatları haricinde, kardiyopulmoner baypas (KPB) kullanılan tüm yetişkin açık kalp ameliyatı olguları çalışmamıza dâhil edildi. 2017 yılında 1200 hasta arasında postoperatif kanama nedeniyle 24 saat içinde en az bir ameliyat geçiren 77 hasta incelendi. Kanamaları cerrahi ve koagülopatik olarak sınıflandırıldı. Revizyon sırasında devam eden aktif kanama ve/veya sızma olmaksızın hematom varlığı koagülopatik kanama olarak tanımlandı. Cerrahi kanama ise sütür veya klips gerektiren spesifik kanamalar olarak tanımlandı. Bulgular: Postoperatif kanama nedeniyle 24 saat içinde en az bir operasyon geçiren 77 (%6,4) hastanın 71'inin tam verilerine ulaşılabildi. Yirmi sekiz (%39.5) hastada cerrahi kanama ve 43 (%60.5) hastada koagülopatik kanama belirlendi. Preoperatif ve intraoperatif dönemde kanama tipi açısından risk faktörü olabilecek değişkenler analiz edildi ancak ilişkili faktör bulunmadı. Sonuç: Hastaların %39.5'inde cerrahi kanama tespit edildi. Literatürde diğer serilerde %56.4 oranında cerrahi kanama oranı saptandı. Deneyimi yüksek olan kalp merkezimizde cerrahi kanama oranı, koagülopati kanamasına göre daha düşük saptandı, az hasta sayısı nedeniyle risk faktörlerini ayırt etmek mümkün olmadı.
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