Acute appendicitis is most common acute surgical interventional condition of abdomen which occurs mostly in 2 nd and 3 rd decade of life. Routine dilatory habit, life style, socio-economic status, familial susceptibility and other factors may etiological indication of appendicitis. In this condition mucosal inflammation and lymphatic hyperplasia combinedly cause partial inflammation of peritoneum. Sometime perforation and ulceration, lodge fecal material in cavity or extravasation take place in cavity which clearly indicates sever and serious condition occurs. In such condition if immediately not treated than it may progress to septic perforation. In initially indicated symptoms are nausea, vomiting, right iliac fossa (RIF) / right upper quadrate region pain and tenderness which diffuse whole abdomen. Rarely fatal condition can develop. Here presenting a case of Mr. Xx, age 29 yrs. old Male having diagnose case of subacute appendicitis. According to Hahnemann aphorism no. 99 "On the whole, detailed to him" [1,3,4] .

In type 1 DM there are destruction of pancreatic islet B cells by autoimmune process in 95% of cases and rest of 5% case by idiopathic cause. Due to complete fail to synthesis of insulin; difficult to manage glucose level and simultaneously increase glucagon level in plasma that results in sever complication in body. Insulin therapy, diet management and regular exercise is the part of management of this disease. According to Hahnemann's 2 nd aphorism and homoeopathic antimiasmatic treatment it is easy to reduce insulin therapeutic dose and to prevent complication. A case of 29-year-old male, came to us for recurrent hypoglycemic attack with high pitched voice. The present case study is focused on how antimiasmatic medicine will help in preventing complications reducing insulin dose and better prognosis with scientific evidences.