All the above derangements confirm that ST is cutaneous findings frequently associated with obesity and dyslipidemia. Thus follow-up of these patients with regard to the development of diseases associated with atherosclerosis may be beneficial.

Our results suggest that an elevated ratio of anti-ox-LDL/ox-LDL can serve as a composite parameter reflecting the total oxidative lipoprotein burden and cardiovascular risk in psoriasis patients.

Our results indicate that psoriasis, especially the severe variants, are associated with increased oxidative stress and dyslipidemia, which correlate positively with atherogenic index and hence, an increased cardiovascular risk.

Background: Non-alcoholic fatty liver disease (NAFLD) is a common liver disease associated with diabetes and cardiovascular risk. Platelets play a vital role in hemostasis and mean platelet volume (MPV) is a measure of average size and platelet activity. Larger platelets are highly thrombogenic. Increase in MPV is well documented in diabetes mellitus (DM). Hence, MPV can be used as simple and cost-effective hematological parameter for predicting cardiovascular events in metabolic syndrome. The present study was conducted to study significance of MPV in NAFLD in type 2 DM (T2 DM). Materials & Methods:A case-control study was conducted on 97 T2 DM patients. They were divided into: group 1 which included T2 DM patients without NAFLD and group 2 with T2 DM patients with NAFLD. Healthy 78 individuals were taken as controls. Serum was used for estimation of fasting and post-prandial blood sugar (FBS & PPBS) and liver function test (LFT). EDTA anticoagulated blood was used for estimation of mean platelet volume (MPV). Results: Among 97 T2 DM patients, 62 were males (63.9%) and 35 were females (36%). Liver size, liver enzymes such as aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) were significantly increased in T2DM patients compared to controls and same were significantly increased in T2DM patients with NAFLD compared to those without NAFLD. MPV was found to be increased in T2 DM patients compared to controls. It was also noted to be increased in T2 DM patients with NAFLD compared to T2 DM patients without NAFLD but there was no statistical significance. Conclusion: MPV should be included as screening test to predict cardiovascular events in T2 DM patients with NAFLD.

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