Objectives: to analyze both frequency and risk factors for seroconversion among newborns of HIV-positive mothers to HIV. Methods: a cohort study was conducted with children residing in Southern Region of Santa Catarina. Secondary data from the notification files and medical records of newborn's mothers of infected infants were used. The participants were all the newborns from 2005 to 2015 that were exposed to HIV through vertical transmission and attended a municipal health care center. Results: there were 104 cases of infant exposure to HIV. Seroconversion was confirmed in three cases, two of them died of AIDS during the study period. Breastfeeding (PR= 32.7; CI95%= 10.7-99.5; p= 0.002) and non-use of antiretroviral drugs during pregnancy (PR=18.2; CI95%= 2.0-163.0; p= 0.008) were risk factors for HIV seroconversion. Conclusions: seroconversion rates among neonates in Southern Region of Santa Catarina were similar to the national average. Seroconversion was associated with non-use of antiretroviral therapy during pregnancy and breastfeeding.

Introduction: We evaluated the epidemiological and clinical profile of reported cases of bee sting incidents in Santa Catarina, Brazil. Methods: This retrospective cohort study included all reported cases of bee sting incidents among the population of Santa Catarina from 2007 to 2017. Results: In total, 8,912 cases were reported, corresponding to an overall rate of 12.3/100,000 population. The mean age was 29,8 years with 60.2% men. The lethality rate was 0.2%. Conclusions: Santa Catarina has a high incidence rate of bee stings, which is higher than the national average. The data presented in this study may be underestimated.

IntroductionIn Brazil, 92,210 HIV-infected pregnant women were notified from 2000 through June 2015, most of whom living in the Southeast (40.5%) and South (30.8%). Detection rates of pregnant women living with HIV in Brazil have increased in the last ten years. In 2005, rates of seropositivity for newborns were as high as 2.0 cases per 1000 live births, which increased to 2.6 in 2014, indicating a 30.0% rise. The aim of this study was to analyse the frequency of seroconversion among newborns to HIV-positive mothers living in southern Santa Catarina, Brazil, from 2005 through 2015.MethodsA cross-sectional study was conducted to collect secondary data. All the newborns that were exposed to HIV by vertical transmission, and attended the municipal healthcare centre between 2005–2015 participated in the study. The study included all infants between 0 and 18 months of age, exposed to HIV vertically, who attended the healthcare centre that serves 18 municipalities in southern Santa Catarina, Brazil, over the 2005–2015 period.ResultsDuring the study period, there were 93 exposures to HIV, of which 3 (3.2%) seroconversions were confirmed and 2 (2.1%) died of AIDS during the follow-up period. Seroconversion was associated with breastfeeding (PR=29.3; 95% CI=9.6–89.2; p=0.002) and the lack of antiretroviral therapy during pregnancy (PR=21.0; 95% CI=2.4–184.5; p=0.006).ConclusionThe results from this study allowed us to conclude that seroconversion among newborns was 5.4%, resulting in a rate of 3.4 cases per 1000 live births, which was higher than the national average. Seroconversion was associated with breastfeeding and the lack of antiretroviral therapy during pregnancy.

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Background: Basal cell carcinoma (BCC) is the most frequent skin neoplasm in Brazil, with increased incidence in the last decades. There are few studies from the Southern Region of Santa Catarina on the epidemiological profile of this tumor. Objectives: To establish epidemiological data on BCC in the Association of Municipalities of the Region of Laguna / SC (AMUREL). Methodology: An observational study with a cross-sectional analysis with positive anatomicopathological reports for BCC between 2009 and 2017 was carried out in a laboratory in Tubarão (SC). The variables collected were year of diagnosis, age, gender, city of origin, location of the lesion, histological subtype, lesion diameter and marginal compromise. Results: A total of 4,125 reports were identified, with a diagnosis of BCC in the AMUREL region with a predominance in men, with a higher frequency in the age group ranging from 61 to 80 years of age and located mainly in the encephalic and cervical regions, being the nodular subtype the most prevalent. A BCC incidence coefficient was found of 93.95 in 2009 and 161.86/100,000 inhabitants in 2017, resulting in an increase of 72%. Limitations of the study:The study was collected in only one laboratory in the stipulated region. Conclusions: A total of 4,125 people were diagnosed with BCC in the AMUREL region, with an incidence increase of 72% in 2009, when compared to 2017. In both genders, the sclerodermiform subtype had the highest frequency in relation to the marginal impairment. There was a prevalence of margins impaired after resection in 29% of the lesions, and a diameter ≤ 2 cm was the most found.