Studies of the porous structure of the polymeric microspheres synthesized from di(p-acrylic phenyl)sulphone (DAS), (p-hydroxyphenyl-p-acrylic phenyl)sulphone (HAS) and divinylbenzene (DVB) are presented. The porous structure was characterized by the nitrogen adsorption method, inverse exclusion chromatography and atomic force microscopy. To describe the tendency of the microspheres to swell, the swelling propensities and the swellability coefficient were also determined.The results show that both polymers studied can be used as packing materials in chromatography. Their porous structures are relatively stable since they are characterized by a high degree of crosslinking. In addition, the polymer ASP-OH containing reactive hydroxyl functional groups provides a convenient starting material for chemical modifications.

ABSTRACT:The preparation of a new chiral polymeric stationary phase for chromatography is presented. A porous copolymer of mono-and dimethacrylate derivatives of bisphenol-S and divinylbenzene containing hydroxyl functional groups was used as a matrix. (3-Aminopropyl)triethoxysilane was used as a coupling agent and was bonded to these groups. The obtained compound was transferred into a final product during a three-step synthesis. The properties of the obtained polymeric phase with the chiral moiety were studied.

A new polymeric stationary phase with potential chiral properties, obtained by the chemical modification of the parent copolymer of dimethacrylate esters of bisphenol S and divinylbenzene, is presented. Hydroxyl functional groups present in the copolymer chemical structure are blocked by optically active selectors of (R,R)‐tartramide derivatives. The influence of the chemical modification of the parent copolymer on its porous structure has been studied. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 2566–2574, 2004

The synthesis and principal properties of 2‐thionaphthenylthioacetic acid (IIIa) and ‐sulfinylacetic acid (IIIb) as well as some of their derivatives are described (yields in g).

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