The results of a comprehensive examination and treatment of a patient with new coronavirus infection COVID-19 showed the possibility of the patient recovering without the use of certain groups of drugs used to treat this disease in accordance with temporary guidelines at the time of the analysis of the clinical case. There is an attempt to define the role of the close ones and their presence at all stages of the treatment in a favorable outcome. Most people want to take care of a relative having a severe form of the disease. Thus, it is necessary to develop an algorithm for visiting the patient by near relations in the hospital. The course of the new coronavirus infection in a particular case, the psychological state of the patient's relatives, the fear of prescribing or not prescribing certain drugs, the fear of bringing a loved one to the "point of no return" are analyzed.
Aim. To estimate the effect of anemia of chronic diseases on the processes of cardiovascular system remodeling in patients with dilated cardiomyopathy and ischemic cardiomyopathy. Methods. The study included 27 patients with dilated cardiomyopathy with anemia, 19 with dilated cardiomyopathy without anemia, 11 with ischemic cardiomyopathy with anemia, 34 with ischemic cardiomyopathy without anemia, and 30 healthy individuals. In these comparison groups, peripheral blood, mean corpuscular hemoglobin and mean cell hemoglobin concentration, reticulocytes, serum iron and ferritin were examined. Electrocardiography, echocardiography, scintigraphy and coronary angiography were performed. Results. In all groups identical signs of chronic heart failure class 3 and 4 were found to be predominant, which was confirmed by a significant decrease of blood pressure, stroke volume, ejection fraction, increase of end systolic and diastolic volumes and sizes, as well as left and right atrial size. Patients with dilated and ischemic cardiomyopathy with anemia had decreased hemoglobin, number of erythrocytes and platelets, positive correlation between hemoglobin and serum iron (r=0.49, p=0.000), red blood cells and ferritin (r=0.61, p=0.000), negative correlation between hemoglobin and ferritin (r=-0.51, p=0.02). In ischemic cardiomyopathy with anemia positive correlation was found between hemoglobin and serum iron (r=0.54, p=0.000), erythrocytes and ferritin (r=0.49, p=0.03), negative correlation - between hemoglobin and ferritin (r=0.54, p=0.03). Conclusion. In patients with dilated and ischemic cardiomyopathy no significant effect of anemia of chronic diseases on heart remodeling processes was revealed.
The aim of research was to evaluate the impact of erythrocytoses on processes of cardiovascular system’s remodelling in patients with dilated and ishaemic cardiomyopathies. 35 (42,2%) patients with dilated cardiomyopathy (DCMP) with erythrocytoses, 19 (23,5%) without erythrocytosis, 34 (28,4%) patients with ishaemic cardiomyopathy (ICMP) with erythrocytosis and 50 (60,1%) without erythrocytosis were included in the study. It has been established that erythrocytoses don’t wield major influence on the heart’s haemodynamics, they appear as a consequence of main diseases and not as their reason, which confirms the domination of congestive heart failure’s signs of III-IV stages. In patients with DCMP and ICMP signs of tissue hypoxia were established as well as oxygen reduction in arterial blood to 60,70 ± 1,24 mm Hg in cases of DCMP and 59,60 ± 1,24 mm Hg in cases of ICMP (in verification 75,44 ± 0,93) - p ˂ 0,001. Arguably, erythrocytoses in cases of DCMP and ICMP are a consequence of congestive heart failure, leading to hypoxic erythrocytosis.
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