Anemia is pathological disorder usually caused by mal nutrition and it was very common among feminine gender during gestational period, number of disease and death are also associated with this type of disorder during pregnancy. The major theme of the study is to evaluate the anemic condition along with prescribed medication among females during the period of pregnancy. Descriptive cross-sectional study was carried out for the period of 9 months at various tertiary care hospitals situated in rural areas of Sindh province. Total 273 females with pregnancy along with anemic condition, were selected by purposive sampling method. From total number of study subjects 71% females were diagnosed as anemic, that were further categorized as mild, moderate and severe, depend on their medical condition. It was observed that anemic condition was more common among infancy pregnant females with ages 20-29 years, the number of patients were 209 (76.5%). females with primary or secondary education had more problem of anemia as compared to females with intermediate or graduation. Anemic females with primary education (126), secondary education (73) whereas anemic female with intermediate (46) and with graduation anemic females were only (28). Females with multipara had severe anemic condition as females with primigravida. Anemic condition becomes more severe among females with second or third trimester. Anemic condition among females with 1st trimester was 37, in second trimester 109 whereas in 3rd trimester 127 anemic females were reported. For management of anemia among females with pregnancy depends upon the medication taking by them, number of females was 142, which were taking 3 or 4 medicine, while females with mono pharmacy were 95 and only 36 females were taking various multi vitamin, intravenous Iron supplement and it was concluded that anemia was more common among females resident of rural area due to unawareness regarding anemia and its associated complication. Another major cause was observed was mal nutrition.

Objectives: To find out the risk factors and their effects on mother and fetus in pregnancy with thrombocytopenia. Study Design: Cross sectional study. Setting: Department of Obstetrics and Gynaecology at Liaquat University Hospital Hyderabad. Period: Six months (1st July 2016 to 31st December 2016). Material and Methods: Total 96 patients with gestational age >24 weeks having platelet count below 150X109/L were included in the study. Patients admitted throughout patient clinic department of obstetrics & Gynecology at Liaqat University Hospital. Those patients having platelet count below 150X109/L were registered for study. Proforma filled which include Patients demographics details, gestational age, complete blood count (Having platelet count) other important investigations like coagulation profile (PT, APTT), Ultrasound and LFT noted in proforma SPSS version used for analysis. Descriptive statics were calculated frequency and percentages were drawn for the study. Results: Risk factors related to thrombocytopenia included PIH18 (18.8%), preeclampsia 14(14.6%), eclampsia 10(10.3%), HELLP Syndrome 6(6.3%), Viral Hepatitis 12(12.5%) and in 36(37.5%) no risk factors was found. Maternal complication were placental abruption21 (21.8%) post partam hemorrhage 14(14.6%). 7(7.3%) were transferred to ICU and 02(2.1%) maternal death was seen. Fetal outcome include low Apgar score of <6 in 17(17.7%), low birth weight 16(16.7%) and NICU admission 11(11.5%). Conclusion: Thrombocytopenia is a common finding in pregnancy careful diagnosis is important to distinguish serious causes from mild then to manage mother and fetus appropriately. Thrombocytopenia in pregnancy is associated with adverse maternal and fetal outcome in significant number of pregnant woman.

Objectives: The objective of this study was to take a look at main causes associated with highest neonatal morbidity and mortality in neonatal care unit of People’s medical college hospital Nawabshah. Study Design: Retrospective study. Period: January 2015 to December 2015. Setting: Paediatric medicine ward of People’s medical college hospital Nawabshah. Methods: The data collected included; sex, gestational age, postnatal age atadmission, weight at admission, main cause of admission, outcome, cause of death. Results: The number of neonates admitted in NICU was 2863 (14.4%) of the total admissions (19882) to the paediatric unit including neonatal unit during the study period. There were more males 1750 (61.9%) than females. Prematurity, neonatal sepsis and birth asphyxia were the most common morbidities (27.5%, 14.9% and 14.6%, respectively). The overall mortality was 21.93% (628 out of 2863 babies). The morbidities with the highest mortality were birth asphyxia 244(38.85%), neonatal sepsis and meningitis 77 (12.26%), and V.L.B.W (9.03%). Conclusion: Birth Asphyxia, neonatal sepsis and meningitis, and low birth weight were the major contributors in admission as well as mortality of newborns, depicting a lack of care and attention in antenatal duration and there is a major lack of training and retraining of birth attendants.

Objectives:The main objective of this study was to look at the burden of neonates, who develop hyperbilirubinemia and the cause of hyperbilirubenemia in these neonates.Setting: Neonatal Unit of Pediatric Ward of PMC Hospital, Nawabshah. Study Design:Observational study.Period:Jan 2016 to December 2016. Materials and Methods:Total 194 neonates were found to have hyperbilirubinemia, out of 2863 babies admitted during this period. Files of these neonates were taken and following data was extracted regarding total, direct and indirect bilirubin, blood groups and Rh typing. In selected cases following investigations were also done: TORCH profile, Urine D/R, Thyroid profile and Ultrasound abdomen.Result:194 babies out of 2863 admissions in neonatal unit were treated as hyperbilirubinemia. 108 babies were male and 86 were females. Regarding the gestational age, 56 babies were preterm and 138 were full term babies.Among various causes of hyperbilirubinemia, physiological jaundice was seen in 109 patients, 22 were having direct hyperbilirubinemia, 36 were due to blood group incompatibility, 15 were due to birth injuries, 4 were having hypothyroidism and 2 were labeled as breast milk jaundice. In 6 patients no single cause was pointed out.Conclusion:Hyperbilirubinemia is still a main cause for admissions in NICU, among the causes of hyperbilirubinemia physiologic jaundice was most common. Prematurity predisposes to aggravating hyperbilirubinemia and its complications.