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Present research work represents antiviral and antibacterial value of body fat of Saara hardwickii commonly called as spiny tailed lizard. Oil was extracted from body fats located in the ventral region of this animal using hydrocarbons e.g., n-hexane, methanol, butanol and ethyl acetate as a solvent. The antibacterial activity of lizard oil was tested against standard as well as multi-resistant lines ofEscherichia coli, Styphalococcus aureus, Pseudomonas aeruginosa and Proteus vulgaris alone and with antibiotic ampicillin. For antibacterial potential, Ethyl acetate and Butanol solvent extract showed best zone of inhibition (7mm) with P. aeruginosa and S. aureus respectively. For antiviral potential, Butanol and Methanol extract showed best HA (Hemagglutination) titer of 04 with NDV and IBV viral strain respectively. It is concluded that lizard oil has antimicrobial potential against different pathogens strains (virus, bacteria).

To cite this paper: Hussain, T., I. Fatima, M.I. Shahzad, M. Rafay, S. Bano and M. Abdullah, 2015 The results indicate that fruits of these plants were more effective in controlling microbes in their aqueous extracts while leaves of these plants were effective in their ethanolic extracts as compared to aqueous and n-hexane extract. In comparison to leaves of these plants, the leaves of D. inoxia was rich source against antimicrobial agents, similarly in comparison of fruits, the fruit of P. minima was best in terms of antimicrobial activities. Overall these plants were most effective against S. aureus and least effective against K. pneumonia in comparison to their antibacterial potentials.

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