O estudo objetivou revisar a literatura sobre a relação entre disfunção temporomandibular (DTM) e fatores psicológicos. Trata-se de uma revisão de literatura com abordagem qualitativa. As bases de dados foram PubMed e BIREME, no período de 2008 a 2018. Como critérios de inclusão: artigos publicados na língua inglesa, com os descritores “temporomandibular joint disorder”, “anxiety”, “depression”, “stress’’ e ‘‘psychological”. Foram excluídos os artigos de revisão de literatura e artigos onde o componente psicológico foi apenas citado e não avaliado propriamente. Caracterizaram-se oito artigos, dos quais os resultados apontaram a correlação significativa entre DTM e comorbidades psicossociais, somáticas e comportamentais. Os fatores psicológicos como somatização, depressão, ansiedade e angústia, principalmente relacionadas ao gênero feminino, configuram um impacto significativo na prevalência de DTM. Nota-se que existe relação aos fatores citados, dessa forma, necessita da assistência interdisciplinar em virtude da natureza físico-psicológica, ou seja, participação da psicologia para intensificação do tratamento odontológico.
The purpose of this article is to report a clinical case of a patient with TMD, evaluating the efficacy of dry needling as a treatment. The study was carried out in a dental clinic of higher education, where the evaluation of the patient was performed in order to conclude a correct diagnosis complementing with the use of dry needling. Patient, female, 38 years old, reported pain throughout the muscular region of the face, where it was more pronounced in the parotid-massometric region, with spreading to the temporal region. After performing the evaluation in addition to the percussion and palpation tests, the patient was diagnosed with spreading myofascial pain, in addition to headache attributed to TMD bilaterally. As a therapeutic approach, the dry needling technique was performed, in addition to the orientation of Cognitive Behavioral Therapy, since the patient reported having parafunctional habits. The techniques used produced an effective improvement to the patient, where the patient reports a relief of the muscular pains when performing the dry needling.
O objetivo do estudo foi evidenciar a expressão imuno-histoquímica da via wnt/b-catenina em células de carcinomas orais (OSCC), por meio de uma revisão da literatura. Para isso, foi realizado uma busca nos bancos de dados PubMed e SciELO com as paravras chaves “β-catenin”, “oral squamous cell carcinoma”, “OSCC” e “Wnt signaling” com operador booleano AND. Como critérios de inclusão adotaram-se artigos publicados na língua inglesa, artigos in vitro, in situ ou ensaios clínicos dos anos de 2010 a 2021 que relacionam a via de sinalização WNT canônica com oral squamous cell carcinoma e os critérios de exclusão considerados foram artigos duplicados, revisão de literatura e que não abordavam a temática. Após a leitura do título, do resumo, e do conteúdo integral de cada um dos estudos, foram selecionados 110 artigos. Compostos de IncRNA, enzimas, derivados de hexaclorofeno e a lignina isolada de Taiwania foram capazes de suprimir o crescimento e metástases pela inibição da via WNT/ β-catenina. Células-tronco cancerosas, enzimas tipo PON2, ingestão de nicotina, citocina TNF-α e gene FAD1 são capazes de aumentar o crescimento e metástase pela inibição da mesma via. Portanto, a expressão desses biomarcadores pode influenciar o prognóstico das células cancerígenas e ajudar os profissionais a explorar novos possíveis efeitos terapêuticos em OSSC modulando a via Wnt / β-catenina.
The study investigated allogenic pulp transplantation as an innovative method of regenerative endodontic therapy. Three patients were selected for the endodontic treatment of single-root teeth, who also had a son/daughter with deciduous teeth or third molars scheduled for extraction. Receptor teeth were endodontically instrumented and irrigated using a tri-antibiotic solution. During the transplant procedures, the teeth from the son/daughter were extracted, sectioned, and the pulp was carefully removed. The harvested pulp from the donor was inserted into the root canal of the host tooth (father/mother), followed by direct pulp capping and resin composite restoration. The teeth were followed-up with for 2 years and were surveyed with computed tomography, the electric pulp vitality test, and Doppler ultrasound examination. At the 6-month follow-up, positive pulp vitality and the formation of periapical lesions were verified in cases 1 and 2. Case 3 showed remarkable periapical radiolucency before transplantation, but after 1 year, such lesions disappeared and there was positive vitality. All teeth were revascularized as determined by Doppler imaging after 2 years with no signs of endodontic/periodontal radiolucency. In conclusion, although this was a case series with only three patients and four teeth treated, it is possible to suppose that this allogenic pulp transplantation protocol could represent a potential strategy for pulp revitalization in specific endodontic cases.
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