No abstract

No abstract

No abstract

No abstract

6.7%) patients had positive SC only, 5 (16.7%) had both positive SC and USB, and 5 (16.7%) patients had USB positive only. The concordance between USB and SC result was moderate (K[0.43). USB brought a percentage increase in diagnosis of this population of 71%. In case of positive URS, 14/24 (58.3%) lesion biopsies, 13/24 (54.1%) SC and 13/24 (54.1%) USB were positive. Out of 10 negative lesion biopsies, 6 (60%) patients had a positive SC. Lesion biopsy histology resulted low-grade in 10/14 (71.4%), high-grade in 3/14 (21.4%) and CIS in 1/14 (7.1%). USB resulted positive in 9/14 (62.3%) of those who had positive lesion biopsies. Among patients with low-grade lesion biopsy, USB showed multifocal low-grade disease in 5/10 (50%) cases and CIS in 1/10 (10%) cases. 2/3 patients with highgrade disease at lesion biopsy showed multifocal UTUC at USB. USB and lesion biopsy were concordant in the diagnosis of the only case with CIS.CONCLUSIONS: The endoscopic diagnosis of UTUC should rely on lesion biopsy, SC and USB. In negative URS, USB may significantly increase the diagnostic rate of UTUC. In positive URS, SC may help providing a pathological diagnosis in negative biopsies. On the other hand, USB helps the characterization of the disease and, thus, may potentially influence its management.