The Japanese version of the DN4 was found to be a helpful tool for discriminating between neuropathic and non-neuropathic pain.

Bolus crystalloid infusion exceeding 80 ml kg(-1) h(-1) may not increase effectiveness of fluid resuscitation. Crystalloid resuscitation for more than 2 h may be detrimental in view of an excessive net fluid retention.

No abstract

Background: Although Spinal Cord Stimulation (SCS) is selected for chronic intractable pain treatment in patients with Failed Back Surgery Syndrome (FBSS), the long-term outcome still remains controversial.

Background: Methadone is an effective long acting opioid analgesic used to manage nociceptive and neuropathic pain. Its unique lipophilic properties, absence of active metabolites and high volume of distribution allows for delivery routes that are unique and innovative enabling patients uninterrupted and effective pain control at the end of life.