Objetivo: Investigar o que a literatura revela sobre a influência da prática musical em habilidades do Processamento Auditivo Central (PAC), e se o tempo de exposição à música atua de alguma maneira nestas competências. Método: A coleta dos artigos foi realizada a partir das bases de dados PubMed, Science Direct e Lilacs, com a combinação de descritores indexados no Medical Subject Headings (MeSH). Critérios de seleção: Foram selecionados artigos em inglês e português, publicados entre os anos de 2010 e 2016, cujo título, ou resumo, ou corpo do trabalho, tivessem relação com o objetivo do presente estudo. Foram excluídos os artigos repetidos e os que não possuíam o resumo ou texto completo, artigos de revisão, dissertações e teses. Análise dos dados: Após a leitura dos artigos na íntegra, foram extraídos os seguintes dados: título, ano de publicação, país de origem, idade e características dos indivíduos da amostra, tipo de estudo, tempo de experiência dos músicos, objetivo da pesquisa, habilidades do PAC avaliadas, resultados encontrados e conclusão. Resultados: A pesquisa realizada gerou o total de 1445 artigos, sendo que 896 deles estavam contidos na Pubmed, 518 na base ScienceDirect e 31 na Lilacs. Ao final da análise, os juízes selecionaram 17 estudos. Conclusão: Os artigos mencionados demonstraram que a prática musical influencia positivamente as habilidades do PAC, não havendo um consenso quanto à atuação do tempo de exposição sobre essas competências, mas evidenciando um melhor resultado de indivíduos com maior experiência musical.

Background: Primary Progressive Aphasia (PPA) is characterized by progressive language impairment due to focal degeneration of brain areas related to linguistic processing. The detection and differential diagnosis of PPA can be difficult with clinical features that may overlap with features of other neurological conditions, such as Alzheimer's disease (AD). The scientific production on PPA in Latin American patients is still scarce. This study investigated the first symptoms in a Brazilian sample of patients with PPA in comparison with AD patients.Method: We compared the first symptoms reported by caregivers of people with PPA (n = 20; semantic variant n = 8, non-fluent variant n = 7, logopenic variant n = 3, and unclassified cases n = 2) and AD (n = 16). Data were collected through the application of a structured questionnaire that was presented in an interview format to the caregiver who knew the patient best.Results: Anomia, paraphasias and motor speech difficulties were the first symptoms capable of differentiating patients with PPA from those with AD, while memory was exclusive of AD. Among the PPA variants, anomia was the initial symptom associated with the semantic variant, while motor speech difficulties were associated with the non-fluent variant. The results are discussed considering the unique cultural and sociodemographic characteristics of this studied population.Conclusion: This study demonstrated that some of the initial symptoms of PPA patients may be unique to clinical variants of PPA and of AD, and their investigation may be useful for the early and differential diagnosis of this population.

Primary Progressive Aphasia (PPA) is a neurological syndrome characterized by impaired language due to neurodegeneration. It is subdivided into three variants: semantic, agrammatic or nonfluent, and logopenic. Pieces of evidence have suggested that learning disabilities in childhood, such as dyslexia, might be susceptibility factors in the occurrence of PPA in adulthood. The objective of this study was to verify the existence of the relationship between PPA and the history of learning disabilities of patients and their children, compared to a control group of individuals with Alzheimer's disease (AD). A questionnaire was applied to investigate the presence of indicators of learning disabilities and difficulties in individuals with PPA and AD and their children. Twenty subjects with PPA and 16 with AD participated in the study. Our findings are presented and discussed in light of the current scientific evidence and the social, educational, and economic Brazilian scenario. Despite the challenges of doing research with individuals with PPA in Brazil, we present the first evidence about the investigation of association between the history of learning disabilities and difficulties and PPA in native Brazilian Portuguese speakers.