Currently, the problem of antibiotic resistance is acute at the world level. As a result of unsystematic and uncontrolled intake of antimicrobial drugs into the human body, pathogenic and opportunistic microorganisms acquire resistance to the action of drugs, and therapy is ineffective. Antibiotic resistance develops as a result of non-compliance with the course of treatment, dosage of drugs, as well as when antibiotics enter the body, residual amounts of which circulate in the external environment and are found in food. The use of antimicrobial agents in agriculture is of great importance. In 2017, Decree of the Government of the Russian Federation No. 2045-r On approval of the Strategy for preventing the spread of antimicrobial resistance in the Russian Federation for the period up to 2030 and the action plan for its implementation came into force, in accordance with which the SCAMP program was developed - a system for monitoring antimicrobial drugs. This program is currently being implemented within the framework of voluntary certification and provides for the achievement of the therapeutic efficacy of antibiotic therapy; reduction in the use of antibiotics; rejection of unsystematic and uncontrolled use of antibiotics for prevention, stimulation of growth and productivity; obtaining raw materials of animal origin and products that do not contain residual amounts of antimicrobial drugs; ensuring food security. A high role in the control system of antimicrobial drugs is played by digitalization in the circulation of food products on the territory of the Russian Federation, which makes it possible to control the turnover from farm to table and to nullify the cases of circulation of unsafe counterfeit products, and the registration of manufacturers in electronic systems and the assignment of a unique digital labeling of products will oblige manufacturers to comply with the requirements of regulatory and technical documentation, including when using medicines.