A significant association between CYP2C9 (*1,*2,*3) genotype and VKORC1 (1639 G>A) haplotype status has been found with increased bleeding tendency to warfarin. This may help to individualize therapy.
Respiratory distress is one of the leading causes of neonatal morbidity and mortality. Factors such as gestational age at birth, pulmonary maturity, and congenital factors are peculiar to this demographic. Clinical evaluation accompanied by chest radiography is the standard protocol for evaluating the underlying causative factors. Knowledge of the radiographic appearances of various pathologies and associations with certain congenital factors is quintessential for radiologists and primary neonatal care providers to steer the management in the right direction.
The impact of the global pandemic due to novel Coronavirus Disease (nCOVID-19) has been braced by all medical subspecialties, including the radiology department. As Computerised Tomography (CT) of the chest as well as radiographs gain more and more importance in diagnosing, following up and prognosticating this respiratory infection, it becomes essential to have set protocols in place regarding imaging, disinfection and departmental workflow to ensure smooth functioning and protection of patients and health care workers. We have formulated the “AMMO” protocol as a guide to smooth functioning of the radiology department, which enumerates the steps to be taken for organisation of patient workload, organising equipment, disinfection protocols, maintaining the health and safety of radiology healthcare workers along with timely and accurate reporting. By combining the established guidelines and the knowledge gained from our experience at a dedicated COVID-19 hospital, this article aims to provide a reference in the management of radiology departments during this pandemic.
Carotidynia is a controversial clinicopathological entity vastly described in Western literature as neck pain in the region of carotid bifurcation secondary to an underlying inflammatory etiology. Radiologically, this appears as perivascular inflammation and has recently been designated as transient perivascular inflammation of the carotid artery (TIPIC) syndrome. The authors of this report discuss the multimodality imaging features of a rare case of this disease in our country to familiarize radiologists with the imaging findings and to encourage the inclusion of TIPIC syndrome as a differential diagnosis for focal neck pain.
Central nervous system (CNS) lymphoma is of two types: primary and secondary (more common). Primary CNS lymphoma usually presents as parenchymal lesions having characteristic imaging findings and may be associated with leptomeningeal involvement. Involvement of multiple cranial nerves as the initial manifestation of primary CNS lymphoma with the development of typical parenchymal lesions on follow-up is a rare entity. This nerve involvement is termed as neurolymphomatosis. We present the magnetic resonance imaging features of five patients presenting with neurolymphomatosis due to non-Hodgkin's lymphoma.
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