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Port-wine stain (PWS) is a congenital capillary malformation commonly found in the head and neck. With an incidence of 0.3%-0.9% in the newborns, this pathological condition affects males and females equally. 1,2 PWS lesions first appear as pink or red macules that do not undergo spontaneous involution and may progressively darken to reddish purple. 3 The lesions grow proportionately with age and can lead to the formation of papules and nodules or may develop into hypertrophic PWS. 4 Aside from cosmetic disfigurement, PWS hypertrophy may also impair sight, speech, nasal breathing, and hearing. 5 PWS is also associated with two uncommon syndromes: Sturge-Weber syndrome (SWS) and Klippel-Trenaunay syndrome (KTS). 6 SWS is a neurocutaneous disorder characterized by PWS usually affecting one hemiface along one or more trigeminal

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Introduction Port-wine stain (PWS) is a progressive capillary malformation that does not resolve spontaneously without treatment. Pulsed dye laser (PDL) is currently the gold standard treatment for PWS, although it is difficult to attain complete clearance and recurrences are common. This study determined the cost-effectiveness of PDL treatment among Thai patients with facial PWS. Methods This was a retrospective chart review of 109 Thai patients with facial PWS and treated with PDL at Siriraj Hospital, Thailand from January 2008 to December 2017. The primary outcome of the study was the cost-effectiveness of PDL treatment in the clinical improvement of facial PWS. Results Ten PDL treatment sessions will have an expected clinical improvement of 60%. At the 10th treatment, the marginal incremental improvement with respect to visit is approximately equal to one. The succeeding treatment sessions will only give an additional improvement of 5–10%. Conclusion A total of 10 PDL treatment sessions was considered cost-effective as it can achieve 60% clinical improvement among Thai patients with facial PWS.