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A (chromatographic) lipophilicity parameters of newly synthesized 2,4-bis(substituted)-6-chloro-s-triazines were studied. PCA-HCA were performed in order to classify and organize various chromatographic lipophilicity parameters that were determined by using different stationary and mobile phases and by various chromatographic techniques. The PCA-HCA indicates that for the set of investigated compounds, similar lipophilicity scales are given by chromatographic systems with covalently bonded hydrocarbons as a stationary phase and acetonitrile as a mobile phase modifier. Another cluster of lipophilicity scales forms cyano and octadecylsilica stationary phases with dioxane or tetrahydrofuran as a mobile phase modifiers. The general arrangement of investigated compounds along PC1 was according to the increase in lipophilicity forming two clusters (one of lower and the other of higher lipophilicity). PCA study of R M values underline the differences concerning solvent fraction. Also reveal that HPTLC systems on amino plates are distinguishable from the cyano and octadecylsilica supports, which were similar.

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