Application of N,N-dimethylhydrazoneprotective group for synthesis of C-phosphorylated aldehydes of the pyrrole series was studied. Removal of the hydrazone protection in monophosphorylated pyrrolylcarbaldehyde hydrazones occurs smoothly, while in biphosphorylated derivatives it results in nitrile formation.

Organo-phosphorus compoundsOrgano-phosphorus compounds S 0080 C-Phosphorylated Pyrrolylcarbaldehydes. -The application of an N,N-dimethylhydrazone protective group for the synthesis of C-phosphorylated aldehydes of the pyrrole series is studied. Removal of the hydrazone protection in monophosphorylated pyrrolylcarbaldehyde hydrazones occurs smoothly [→ (VII), (X)], while in biphosphorylated derivatives, it results in nitrile formation [→ (IV)]. -(IVONIN*, S. P.; TOLMACHEV, A. A.; TERIKOVSKA, T. E.; ANISHCHENKO, A. A.; CHAIKOVSKAYA, A. A.; PINCHUK, A. M.; Heteroat. Chem. 14 (2003) 3, 258-261; Dnepropetrovsk State Univ., Dnepropetrovsk 320625, Ukraine; Eng.) -M. Kowall 31-197