Exploration of the hyperspectral domain offers a host of new research and application possibilities involving material appearance modeling. In this article, we address these prospects with respect to human skin, one of the most ubiquitous materials portrayed in synthetic imaging. We present the first hyperspectral model designed for the predictive rendering of skin appearance attributes in the ultraviolet, visible, and infrared domains. The proposed model incorporates the intrinsic bio-optical properties of human skin affecting light transport in these spectral regions, including the particle nature and distribution patterns of the main light attenuation agents found within the cutaneous tissues. Accordingly, it accounts for phenomena that significantly affect skin spectral signatures, both within and outside the visible domain, such as detour and sieve effects, that are overlooked by existing skin appearance models. Using a first-principles approach, the proposed model computes the surface and subsurface scattering components of skin reflectance taking into account not only the wavelength and the illumination geometry, but also the positional dependence of the reflected light. Hence, the spectral and spatial distributions of light interacting with human skin can be comprehensively represented in terms of hyperspectral reflectance and BSSRDF, respectively.

No abstract

Abstract. There are several pathologies whose study and diagnosis is impaired by a relatively small number of documented cases. A practical approach to overcome this obstacle and advance the research in this area consists in employing computer simulations to perform controlled in silico experiments. The results of these experiments, in turn, may be incorporated in the design of differential protocols for these pathologies. Accordingly, in this paper, we investigate the spectral responses of human skin affected by the presence of abnormal amounts of two dysfunctional hemoglobins, methemoglobin and sulfhemoglobin, which are associated with two life-threatening medical conditions, methemoglobinemia and sulfhemoglobinemia, respectively. We analyze the results of our in silico experiments and discuss their potential applications to the development of more effective noninvasive monitoring and differentiation procedures for these medical conditions.

Abstract. Anemia is a prevalent medical condition that seriously affects millions of people all over the world. In many regions, not only its initial detection but also its monitoring are hindered by limited access to laboratory facilities. This situation has motivated the development of a wide range of optical devices and procedures to assist physicians in these tasks. Although noticeable progress has been achieved in this area, the search for reliable, low-cost, and risk-free solutions still continues, and the strengthening of the knowledge base about this disorder and its effects is essential for the success of these initiatives. We contribute to these efforts by closely examining the sensitivity of human skin hyperspectral responses (within and outside the visible region of the light spectrum) to reduced hemoglobin concentrations associated with increasing anemia severity levels. This investigation, which involves skin specimens with distinct biophysical and morphological characteristics, is supported by controlled in silico experiments performed using a predictive light transport model and measured data reported in the biomedical literature. We also propose a noninvasive procedure to be employed in the monitoring of this condition at the point-of-care.

Peripheral cyanosis, the purple or blue coloration of hands and feet, can represent the initial signs of life-threatening medical conditions such as heart failure due to coronary occlusion. This makes its effective detection relevant for the timely screening of such conditions. In order to reduce the probability of false negatives during the assessment of peripheral cyanosis, one needs to consider that the manifestation of its characteristic chromatic attributes can be affected by a number of physiological factors, notably cutaneous pigmentation. The extent to which cutaneous pigmentation can impair this assessment has not been experimentally investigated to date, however. Although the detection of peripheral cyanosis in darkly-pigmented individuals has been deemed to be impractical, data to support or refute this assertion are lacking in the literature. In this paper, we address these issues through controlled in silico experiments that allow us to predictively reproduce appearance changes triggered by peripheral cyanosis (at different severity stages) on individuals with distinct levels of cutaneous pigmentation. Our findings indicate that the degree of detection difficulty posed by cutaneous pigmentation can be considerably mitigated by selecting the appropriate skin site to perform the observations.