Background Low back pain (LBP) is well known as the most common musculoskeletal disorder with the lifetime prevalence of eighty percent. Worldwide, 37% of low back pain was attributable to occupational risk factors. Truck driving is one among the jobs causing occupational LBP. Even though these drivers in Ethiopia run the high risk of occupational injuries and illnesses like drivers elsewhere, the evidence that shows the magnitude and factors that contribute to LBP is a significant shortcoming. Objective To assess the magnitude and contributing factors of low back pain among long-distance truck drivers at Modjo Dry Port, Ethiopia, 2018. Methods A cross-sectional study was conducted among systematically selected 422 long-distance truck drivers at Modjo Dry Port, Ethiopia, from February to March 2018. Data were collected through face-to-face individual interview using a structured questionnaire adapted from the standardized Nordic questionnaire for the analysis of musculoskeletal symptoms. The data were entered using EPI-DATA version 4.2.0.0 and cleaned and analyzed using SPSS version 20 statistical software for windows. Binary logistic regression was computed to determine the association using crude and adjusted odds ratios at 95% confidence intervals. Independent variables with a P value less than 0.05 in the multivariable logistic regression model were considered as significant. Results Of 400 truck drivers interviewed, the prevalence of LBP was found to be 65%. The study also found smoking cigarette (AOR = 2.24, 95% CI (1.25–4.01), and P=0.007), physical inactivity (AOR = 2.12, 95% CI (1.28–3.51), and P=0.003), chronic diseases other than LBP (AOR = 2.18, 95% CI (1.32–3.61), and P=0.002), frequent lifting or carrying heavy objects (AOR = 3.02, 95% CI (1.75–5.22), and P ≤ 0.001), perceived improper sitting posture while driving (AOR = 2.20, 95% CI (1.35–3.60), and P=0.002), and perceived job stress (AOR = 2.07, 95% CI (1.20–3.57), and P=0.009) were contributing factors of low back pain. Conclusion This finding shows the public health importance of low back pain among long-distance truck drivers in Ethiopia. Individual factors largely accounted for the development of low back pain; hence, orientation on these modifiable risk factors and regular follow-up on safety procedures should be considered to mitigate the problem.

Background: In Ethiopia, the human papillomavirus vaccine has been introduced since 2018. Since the vaccination program targets girls age 9-13, the success of vaccination depends on the parental decision and their willingness to vaccinate their daughters. Therefore, a study on parental willingness to vaccinate their daughter and factors associated is needed. Objective: To assess parent's willingness to vaccinate their daughter against the human papillomavirus and its associated factors in Bench-Sheko Zone, southwest Ethiopia. Methods: A community-based cross-sectional study was conducted among 502 participants in Bench-Sheko Zone, southwest Ethiopia. The participants were selected using a systematic random sampling method. Frequency tables, mean and standard deviation were used to summarize the data. A binary logistic regression using bivariate and multivariable logistic regression analysis was used to identify factors associated with parental willingness to vaccinate their daughter. The level of significance was declared at P-value < 0.05. Results: Of the 502 participants interviewed, 399 (79.5%), 95% CI (76%, 83%) of parents were willing to vaccinate their daughter. The study found that primary education and above (AOR ¼ 2.9, 95% CI [1.79, 4.95]), having good knowledge (AOR ¼ 2.1, 95% CI [1.15, 4.10]) and positive attitude (AOR ¼ 2, 95% CI [1.30, 3.41]) were significantly associated with parental willingness to vaccinate their daughter. Conclusion:This study found that there was a high parental willingness to vaccinate their daughter against the human papillomavirus in the study area. Primary education and above, having good knowledge and positive attitude were factors associated with parental willingness to vaccinate their daughter. Therefore, providing health information's regarding human papillomavirus vaccination with emphasis to raise community awareness should be designed especially less educated parents need to be targeted.

Background:Poor glycemic control is a major public health issue among patients with type 2 diabetes mellitus and a significant risk factor for the progression of diabetic complications. This study aimed to assess the magnitude and contributing factors of poor glycemic control among type 2 diabetes patients on follow-up at Adama Hospital Medical College (AHMC) in East Ethiopia. Methods: A cross-sectional study was conducted among 245 type 2 diabetes patients on follow-up at AHMC from March 1 to 30, 2020. All type 2 diabetes patients on follow-up at AHMC and fulfilling the inclusion criteria were included in the study. The data were collected through face-to-face interviews using structured questionnaires and reviewing the patient chart. The data were entered and analyzed using SPSS version 21. The level of significance was declared at a p-value of <0.05. Results: Of the 245 type 2 diabetes patients included in the study, 157 (64.1%) had poor glycemic control. The factors associated with poor glycemic control were being male (AOR = 2.28, 95% CI [1.24-4.21]), not attending formal education (AOR = 3.12, 95% CI [1.53-6.35]), monthly income of <136 USD (AOR = 2.14, 95% CI [1.17-3.91]), overweight (AOR = 2.60, 95% CI [1.32-5.10]) and obesity (AOR = 3.44, 95% CI [1.44-8.21]), and chewing khat (AOR = 2.77, 95% CI [1.04-7.33]). Conclusion:The proportion of poor glycemic control among type 2 diabetes patients at AHMC was remarkably high. Therefore, more effort should be taken to strengthening and disseminating health education programs for diabetes patients at each follow-up visit on the importance of achieving optimal body weight, avoiding khat chewing, and maintaining regular physical exercise to prevent and mitigate the complications resulting from poor glycemic control.

Summary Background High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and efficiency of targeting efforts. We aimed to assess HIV incidence and HIV mortality for all second-level administrative units across sub-Saharan Africa. Methods In this modelling study, we developed a framework that used the geographically specific HIV prevalence data collected in seroprevalence surveys and antenatal care clinics to train a model that estimates HIV incidence and mortality among individuals aged 15–49 years. We used a model-based geostatistical framework to estimate HIV prevalence at the second administrative level in 44 countries in sub-Saharan Africa for 2000–18 and sought data on the number of individuals on antiretroviral therapy (ART) by second-level administrative unit. We then modified the Estimation and Projection Package (EPP) to use these HIV prevalence and treatment estimates to estimate HIV incidence and mortality by second-level administrative unit. Findings The estimates suggest substantial variation in HIV incidence and mortality rates both between and within countries in sub-Saharan Africa, with 15 countries having a ten-times or greater difference in estimated HIV incidence between the second-level administrative units with the lowest and highest estimated incidence levels. Across all 44 countries in 2018, HIV incidence ranged from 2·8 (95% uncertainty interval 2·1–3·8) in Mauritania to 1585·9 (1369·4–1824·8) cases per 100 000 people in Lesotho and HIV mortality ranged from 0·8 (0·7–0·9) in Mauritania to 676·5 (513·6–888·0) deaths per 100 000 people in Lesotho. Variation in both incidence and mortality was substantially greater at the subnational level than at the national level and the highest estimated rates were accordingly higher. Among second-level administrative units, Guijá District, Gaza Province, Mozambique, had the highest estimated HIV incidence (4661·7 [2544·8–8120·3]) cases per 100 000 people in 2018 and Inhassunge District, Zambezia Province, Mozambique, had the highest estimated HIV mortality rate (1163·0 [679·0–1866·8]) deaths per 100 000 people. Further, the rate of reduction in HIV incidence and mortality from 2000 to 2018, as well as the ratio of new infections to the number of people living with HIV was highly variable. Although most second-level administrative units had declines in the number of new cases (3316 [81·1%] of 4087 units) and number of deaths (3325 [81·4%]), nearly all appeared well short of the targeted 75% reduction in new cases and deaths between 2010 and 2020. Interpretation Our estimates suggest that most second-level administrative units in sub-Saharan Africa are falling short of the targeted 75% reduction in new cases and deaths by 2020, which is further compounded by substantial within-country variability...

Background: Breast cancer tumours are the most common malignant tumours among women in Ethiopia. Although advanced-stage diagnosis of breast cancer is a common problem, evidence-based information is lacking about the magnitude and determinants of advanced-stage presentation in north-west Ethiopia.Methods: An institution-based, cross-sectional study was conducted at the oncology units of the University of Gondar and Felege Hiwot specialised hospitals. Stages III and IV were considered advanced stage, whereas stages I and II were considered early stages. Data were collected prospectively on newly diagnosed breast cancer patients and entered using the EPI Info version 7.2 and analysed using Statistical Package for the Social Sciences version 23. Multivariable logistic regression was used to identify the determinants of advanced-stage diagnosis of breast cancer. A p-value < 0.05 was used as the cut-off point to select the determinants of the advanced stage.Result: About 71.2% of breast cancer patients presented with advanced-stage disease. The median age of patients was 40 years. Rural residence (adjusted odds ratio (AOR) = 1.7; 95% confidence interval (CI): 1.02, 2.96), painless breast lump/wound (AOR = 2.5; 95% CI: 1.45, 4.13), travel distance ≥5 km (AOR = 3.2; 95% CI: 1.72, 5.29), not practising breast self-examination (BSE) (AOR = 2.9; 95% CI: 1.30, 6.52), time to presentation ≥3 months (AOR = 1.4; 95% CI: 1.02, 2.37) and misdiagnosed at first visit (AOR = 1.9; 95% CI: 1.09, 3.59) were determinants of advanced-stage breast cancer. Conclusion:Nearly three-quarters of the patients were diagnosed with advanced-stage breast cancer. Not practising BSE, travel distance ≥5 km, rural residence, painless breast wound/lump and being misdiagnosed at first visit were important determinants of advanced-stage diagnosis of breast cancer. Focused awareness creation programmes for the public and increasing cancer diagnostic centres in the country are crucial to downstage breast cancer at presentation.