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American Process Inc.’s patented AVAP® technology offers commercial-scale production of nanocellulose with flexibility in final product morphology and surface properties (hydrophilic or hydrophobic) that can service the wide variety of emerging end-use market segments. The novel hydrophobic lignin-coated variety of AVAP nanocellulose can be incorporated into plastics. This achievement overcomes a well-known barrier to commercial utilization of nanocellulose. Furthermore, AVAP nanocellulose is anticipated to be cost competitive with petroleum based polymers as well as polymer additives. This breakthrough technology can help achieve the U.S. Department of Agriculture’s future global market size estimate for nanocellulose.

In the commercial development of novel nanoscale materials, a proactive approach toward safe commercialization requires assessment of material safety for manufacturing, in product use and for environmental impacts. The goal of this study was to design an industrially-relevant testing strategy and develop key data on lignin-coated cellulose nanomaterials to evaluate their safety before widescale market introduction and subsequent commercialization. The testing plan developed to evaluate BioPlus® lignin-coated fibrils (L-CNF) and BioPlus® lignin-coated crystals (L-CNC) considered a range of potential uses, and employed a variety of standard and tailored protocols to characterize physico-chemical properties, human health effects and environmental fate and toxicity. For human health studies, acute oral toxicity testing as well as dermal and eye irritation studies were completed. Results reveal no oral, dermal or ocular toxicity following L-CNC and L-CNF exposure at the highest doses tested. Testing conducted to evaluate potential environmental effects included aquatic toxicity testing of bacteria (Vibrio fisheri), algae (Pseudokirchneriella subcapitata), invertebrates (Daphnia magna), and vertebrates (Danio rerio). A unique aspect of the study was that in general, testing was performed at environmentally relevant concentrations. Virtually no toxic effects were reported for either L-CNC or L-CNF in these tests, even at artificially high concentrations that could not feasibly occur in the environment. Together with published studies examining the effects of related and conventional substances, these results demonstrate that L-CNC and L-CNF are relatively non-toxic for the broad range of endpoints considered, much like their conventional cellulosic counterparts. These results were anticipated, due to the ubiquity of cellulose in commerce and in the environment, however publication of such negative results is rare, yet critically important to further understanding of the disposition of commercially relevant nanoscale materials.

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In this paper we briefly describe pinch technology as a practical tool for effective energy management in the pulp and paper industry. Results indicate good steam savings. Recently pinch technology has been extended to water management. We have developed a customized methodology for the pulp and paper industry, to eliminate or reduce fresh water intake. Although the methodology is not fully developed it is a "proof of concept" that pinch principles can be applied to water related problems. The eventual combination of both thermal and water pinch will thus provide a structured and comprehensive approach for plant wide efficiency increase.