Background
Hepatitis C virus (HCV) infection has been reported among gay, bisexual, and other men who have sex with men (GBM) globally including GBM with human immunodeficiency virus (HIV) and HIV-negative GBM, particularly those using HIV preexposure prophylaxis (PrEP). In Australia, HCV direct-acting antiviral treatment (DAA) was government-funded from 2016. Large implementation studies of PrEP also began in 2016. We examined HCV incidence among GBM to assess whether HCV incidence has changed since 2015.
Methods
Data were drawn from the Australian Collaboration for Coordinated Enhanced Sentinel Surveillance. We included GBM who tested HCV antibody negative at their first test and had ≥1 subsequent test. Generalized linear modeling (Poisson distribution) was used to examine HCV incidence from 2009 to 2019 stratified by HIV status, and among HIV-negative GBM prescribed PrEP from 2016 to 2019.
Results
Among 6744 GBM with HIV, HCV incidence was 1.03 per 100 person-years (PY). Incidence declined by 78% in 2019 compared to 2015 (incidence rate ratio [IRR], 0.22 [95% confidence interval {CI}: .09–.55]). Among 20 590 HIV-negative GBM, HCV incidence was 0.20/100 PY, with no significant change over time. Among 11 661 HIV-negative GBM prescribed PrEP, HCV incidence was 0.29/100 PY. Compared to 2016, incidence among GBM prescribed PrEP declined by 80% in 2019 (IRR, 0.20 [95% CI: .06–.64]).
Conclusions
HCV incidence among GBM living with HIV declined following DAA availability. There was no observed change in HCV incidence among HIV-negative GBM overall. Among GBM prescribed PrEP, incidence declined since the early years of PrEP implementation in Australia. Australia is on track to eliminate HCV among GBM before global 2030 targets.
The paper is dealing with a developed concept named Empowerment Teaching, which is based on practical teaching experience gained in various mining universities. It is demonstrated that this concept can be used to increase the effectiveness of knowledge transfer to mining countries in the world, as well as to overcome cultural barriers between lecturers and their students. The two models of participatory training, which are proposed to be named “physical” and “emotional” models, are portrayed. The authors are convinced that participatory training methods can be an ideal answer to a challenge associated with workers’ competencies in mining, namely – the potential of highly motivated and well-educated young academics is often diminished by a lack of ability to apply their knowledge. A special emphasis is made on the possible application of empowerment teaching for educational and training activities in the field of occupational safety and health (OSH), which is a matter of utmost importance for the mining industry. Several benchmarking initiatives in the field of OSH (“safety culture”, zero-accident vision) are underlined to be encouraged and promoted by means of new teaching methods. The examples of successful international cooperation among universities are given, as well.
By carefully reviewing existing cancer registry records in Vietnam, we identified a larger number of malignant mesothelioma cases than previously estimated. We recommend the use of cancer registry data in tracking future asbestos-related disease in Vietnam.
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