Background and Objectives: To determine the antibiotic resistance rate of H. pylori among patients with peptic ulcer. Materials and Methods: A cross-sectional monocentric study was conducted from January to December 2021 among patients aged from 16 years with gastrointestinal symptoms and esophagogastroduodenoscopy. Gastric mucosa biopsies were collected at the edges of the ulcer or at lesion sites for H. pylori culture. Five antibiotics (amoxicillin (AMX), clarithromycin (CLR), metronidazole (MTZ), levofloxacin (LEV), and tetracycline (TET)) were selected for antibiotic susceptibility testing. Results: One hundred and twenty-five patients were included, and the sex ratio was 0.6. Their mean age was 47.3 ± 14.2 years. All of the participants had gastritis, and 24.0% had duodenitis. A total of 21.6% of patients had a duodenal ulcer, and 12.8% had an antral ulcer. A total of 40 specimens have grown in H. pylori culture. The proportion of resistance to AMX, CLR, MTZ, LEV, and TET was 27.5%, 50%, 67.5%, 35%, and 5%, respectively. The proportion of multidrug resistance was 22.5%. The proportion of double resistance to AMX + CLR was 20.0%, AMX + MTZ was 15.0%, AMX + LEV was 2.5%, CLR + MTZ was 32.5%, and TET + MTZ was 5.0%. Conclusions: Our research results show that the treatment with MTX-TET or LVX-AMOX has the highest sensitivity rate. Therefore, practitioners should refer to these regimes to eradicate H. pylori in patients with gastric and duodenal ulcers. The reports on H. pylori eradication from different geographic areas show heterogeneous results. Therefore, continuous monitoring of antibiotic resistance of H. pylori in each population is very important. Having evidence helps clinicians to treat patients most effectively, reduce treatment costs, and limit the rate of antibiotic resistance.

Aims: To identify the hypertension status and its nutritional associated factors in adults in two coastal communes of Nghe An province. Methods: A cross-sectional study was conducted on 1170 adults aged 40-69 years in Nghi Thinh and Nghi Thai communes, Nghi Loc district, Nghe An province. General information, blood pressure, anthropometry, salt intake behavior, alcohol consumption frequency, and disease history were collected. The hypertensive prevalence was adjusted for age-sex structure of population. Multilogistic regression analysis was applied to test several models for the association of hypertension to socio–economic conditions, body mass index and waist circumference, high salt intake behavior, and frequency of alcohol consumption. Results: The age- and sex-adjusted prevalence (95%CI) of hypertension status was 46.3 (42.6-50.0), 11.3 (9.12-14.0), 18.1 (15.1-21.5), 7.97 (6.11-10.3), 16.3 % (13.7-19.3), respectively, in normal, hight-normal, grade 1 hypertension, grade 2 hypertension, and previous diagnosed with current use of antihypertensive drugs. There were still 61.5% of hypertensive subjects without knowing the condition. The independent associated factors of hypertension were age, sex, obese status, vegetable and fruit intake/day (<5 units/day), high salt intake behavior, alcohol consumption (> 1 time/week), previously diagnosed dyslipidemia and family members with hypertension. Conclusions: The study indicates the high hypertension prevalence in the coastal communes. The most important associated factors for hypertension should be given a great attention in controlling hypertension in the population.