Rhodococcus equi (Prescotella equi;Sangal et al., 2022) is a Grampositive actinomycete, a close relative of pathogenic mycobacteria, and both an environmental soil bacterium and a facultative intracellular pathogen. It can cause life-threatening pulmonary infections in young foals and in immunocompromised humans, particularly in
Rhodococcus equi
is a major cause of life-threatening pneumonia in foals and occasionally in immunocompromised persons. Virulence-associated protein A (VapA) promotes
R. equi
multiplication in lung macrophages, which are the major host cells during foal infection.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.