In this experiment, the use of the OTTLE for determining formal redox potentials, n values, and spectra of redox couples is illustrated by measurements on solutions of ferricyanide and o-tolidine using a variety of electrochemical techniques.

No abstract

No abstract

relates to the directed dipole of a molecule which one could argue would determine the size and shape of the puncture a molecule made in the dipolar membrane of a neuron. Possibly one could even eliminate the necessity of full penetration of the molecule into the interior of the neuron, and hypothesize that the presence of the molecule on the surface and the consequent disordering of the membrane would be sufficient. The second axis correlates to the first u electron excitation energy, which one would expect to correlate to Lewis acidity. Whichever one is chosen, it could possibly be sensed by the effect of the molecule on some biochemical pathway which involved electron transfer. ACKNOWLEDGMENTThe authors thank Dave Kalman, who helped us decipher the CNDO data, Carl Appellof and Jim Koskinen for writing the 3-dimensional model building program, and M. da Koven for moral support. LITERATURE CITEDAn optlcaliy transparent thin-layer electrode (OTTLE) with characterlstics of mercury has been prepared by electrodepositing a thin film of mercury on a 500-lpi gold minigrid. The negative potential range of this Hg-Au OTTLE was 500 mV greater than that obtained on a Au OTTLE and 200 mV greater than that reported for a Hg-NI OllLE. The large hydrogen overvoltage is attributed to the good overvoltage characteristics of the gold substrate, which is quite soluble in mercury, and to the formation of a continuous mercury film rather than droplets. The optical transparency of the gold minigrid (60%) was not measurably diminished by deposition of the mercury film. The extended negative potential range Is useful for observing electrode processes with large negative reduction potentials as illustrated by vitamin BI2 and glyoxyllc acld.

No abstract