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The Human BioMolecular Atlas Program (HuBMAP) aims to create a multi-scale spatial atlas of the healthy human body at single-cell resolution by applying advanced technologies and disseminating resources to the community. As the HuBMAP moves past its first phase, creating ontologies, protocols and pipelines, this Perspective introduces the production phase: the generation of reference spatial maps of functional tissue units across many organs from diverse populations and the creation of mapping tools and infrastructure to advance biomedical research.HuBMAP was founded with the goal of establishing state-of-the-art frameworks for building spatial multiomic maps of non-diseased human organs at single-cell resolution 1 . During the first phase (2018)(2019)(2020)(2021)(2022), the priorities of the project included the validation and development of assay platforms; workflows for data processing, management, exploration and visualization; and the establishment of protocols, quality control standards and standard operating procedures. Extensive infrastructure was established through a coordinated effort among the various HuB-MAP integration, visualization and engagement teams, tissue-mapping centres, technology and tools development and rapid technology implementation teams and working groups 1 . Single-cell maps, predominantly consisting of two-dimensional (2D) spatial data as well as data from dissociated cells, were generated for several organs. The HuBMAP Data Portal (https://portal.hubmapconsortium.org) was established for open access to experimental tissue data and reference atlas data.The infrastructure was augmented with software tools for tissue data registration, processing, annotation, visualization, cell segmentation and automated annotation of cell types and cellular neighbourhoods from spatial data. Computational methods were developed for integrating multiple data types across scales and interpretation 2 . Standard reference terminology and a common coordinate framework spanning anatomical to biomolecular scales were established to ensure interoperability across organs, research groups and consortia 3 . Guidelines to capture high-quality multiplexed spatial data 4 were established including validated panels of cell-and structure-specific antibodies 5 . The first phase produced a large number of manuscripts (https://commonfund.nih.gov/ publications?pid=43) including spatially resolved single-cell maps [6][7][8][9][10][11] .The production phase of HuBMAP was launched in the autumn of 2022. The focus is on scaling data production spanning diverse biological variables (for example, age and ethnicity) and deployment and enhancement of analytical, visualization and navigational tools to generate high-resolution 3D accessible maps of major functional tissue units from more than 20 organs. This phase involves over 60 institutions and 400 researchers with opportunities for active intra-and inter-consortia collaborations and building a foundational resource for new biological insights and precision medicine. Below, ...

Industry and governments have deployed computer vision models to make high-stake decisions in society. While they are often presented as neutral and objective, scholars have recognized that bias in these models might lead to the reproduction of racial, social, cultural and economic inequity. A growing body of work situates the provenance of bias in the collection and annotation of datasets that are needed to train computer vision models. This article moves from studying bias in computer vision models to the agency that is commonly attributed to them: the fact that they are universally seen as being able to make biased decisions. Building on the work of Bruno Latour and Jonathan Crary, the authors discuss computer vision models as agential optical instruments in the production of contemporary visuality. They analyse five interconnected research steps – task selection, category selection, data collection, data labelling and evaluation – of six widely cited benchmark datasets, published during a critical stage in the development of the field (2004–2020): Caltech 101, Caltech 256, PASCAL VOC, ImageNet, MS COCO and Google Open Images. They found that, despite all sorts of justifications, the selection of categories is not based on any general notion of visuality, but depends heavily upon perceived practical applications, the availability of downloadable images and, in conjunction with data collection, favours categories that can be unambiguously described by text. Second, the reliance on Flickr for data collection introduces a temporal bias in computer vision datasets. Third, by comparing aggregate accuracy rates and ‘human’ performance, the dataset papers introduce a false dichotomy between the agency of computer vision models and human observers. In general, the authors argue that the agency of datasets is produced by obscuring the power and subjective choices of its creators and the countless hours of highly disciplined labour of crowd workers.

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This article will demonstrate that digital newspaper archives can be used to shed new light on the historical readership of nineteenth-century newspapers and magazines. The digital newspaper archive of Australia (Trove) was used to study the distribution and reception of the renowned Illustrated London News (ILN) in the Australian colonies between 1842 and 1872. As a result of this research, this article shows that around 17,000 copies of the magazine reached the Australian colonies by each mail in 1862. This corresponds to 8-11% of the total circulation of the ILN at that time so making it the most widely read British publication in the Australian colonies. By means of a case study into the colonial readership of the ILN, this article will argue that the magazine was an important building block in the formation of the imagined communities both of Britain and its dominions in the period between 1842 and 1872. KEYWORDS historical readership; digital newspaper archives; Illustrated London News; imagined communities; Trove To our colonies this Journal has an interest, which can be claimed by no other. The Australian or the Canadian settled in remote districts, (…), looks forward with more pleasure