This paper discusses the principle of SPWM, as well as its mathematical models, highlight introduce the generation principle of SPWM wave based on TI digital signal processor TMS320LF2407A. The formula and mathematical model are simplified by using the symmetric regular sampling method. Update the value of the program by comparing the look-up table, this method improves the operational efficiency, and reduces the error generation. The paper detailed analysis the configuration of each register in event manager module, and gives a critical interrupt subroutine. Through online simulation debugging, get the correct SPWM and the corresponding dead-time waveform.
This paper proposes a multi-virtual-vector model predictive control (MPC) for a dual three-phase permanent magnet synchronous machine (DTP-PMSM), which aims to regulate the currents in both fundamental and harmonic subspace. Apart from the fundamental α-β subspace, the harmonic subspace termed x-y is decoupled in multiphase PMSM according to vector space decomposition (VSD). Hence, the regulation of x-y currents is of paramount importance to improve control performance. In order to take into account both fundamental and harmonic subspaces, this paper presents a multi-virtual-vector model predictive control (MVV-MPC) scheme to significantly improve the steady performance without affecting the dynamic response. In this way, virtual vectors are pre-synthesized to eliminate the components in the x-y subspace and then a vector with adjustable phase and amplitude is composed of two effective virtual vectors and a zero vector. As a result, an enhanced current tracking ability is acquired due to the expanded output range of the voltage vector. Lastly, both simulation and experimental results are given to confirm the feasibility of the proposed MVV-MPC for DTP-PMSM.
We developed an integrin αvβ3-specific liposomes, TR-conjugated liposomes (TR-LPs), loading IR783 for NIR imaging-guided both PTT and PDT. The TR-LPs was composed of soyabeanphosphatidylcholine, cholesterol, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine- N- [methoxy(polyethylene glycol)-2000] (DSPE-PEG) and TR-functionalized DSPE-PEG. IR783, NIR PTT/PDT diagnostic agents, were encapsulated in the hydrophilic core of the TR-LPs. DSPE-PEG had ability of reducing the absorption of TR-LPs by the reticuloendothelial system and increase the cycle time in body. RGD fragment on the TR peptide (TR = c(RGD)-AGYLLGHINLHHLAHL(Aib)HHIL-cys) enhanced the tumor selectivity of liposomes by specifically targeting integrin αvβ3-overexpressing cancer cells. Simultaneously, the rest of fragment on the TR peptide can be changed to the positive charge in the tumor microenvironment (pH 6.5), improving cellular uptake of photoagents at tumor site. We executed a set of in vitro and in vivo experiments to verify if, by functionalizing liposomes with an integrin αvβ3-specific and pH responding peptide, it is possible to achieve NIR imaging guided PTT/PDT for tumor treatment. TR-conjugated liposomes exhibited favorable physical and chemical stability, loading capacity, biocompatibility and tumor targeting. TR-LPs can safely and efficiently delivery IR783 to tumor sites to achieve their therapeutic function. IR783-TR-LPs is promising as a potentially safe and effective phototherapeutic agents for NIR fluorescence-guided tumor therapy applications.
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