This paper describes the development of a mild Pd-catalyzed C–H arylation reaction using potassium aryltrifluoroborates in conjunction with Mn(OAc)3 as the oxidant. The scope of this transformation is explored with a variety of different aryltrifluoroborates and arylpyridine substrates. Preliminary mechanistic studies suggest that the reaction proceeds via a high-valent Pd mechanism with C–H activation occurring at or before the rate determining step.

The development of a mild Pd-catalyzed C-H arylation reaction using potassium aryltrifluoroborates in conjunction with manganese triacetate as the oxidant is described. The scope of this transformation is explored with a variety of different aryltrifluoroborates and arylpyridine substrates. Preliminary mechanistic studies suggest that the reaction proceeds via a high-valent Pd mechanism with C-H activation occurring at or before the rate determining step. -(SEIGERMAN, C. K.; MICYUS, T. M.; NEUFELDT, S. R.; SANFORD*, M. S.; Tetrahedron 69 (2013) 27-28, 5580-5587, http://dx.