Background Breech deliveries have always been topical issues in obstetrics. Neonates undergoing term breech deliveries have long-term morbidity up to the school age irrespective of mode of delivery. Objective To determine prevalence and perinatal outcomes of singleton term breech delivery. Methods Hospital based cross-sectional study was conducted on 384 participants retrospectively. Descriptive and analytical statistics was used. Result A total of 384 breech deliveries were included. Prevalence of singleton breech deliveries in the hospital was 3.4%. The perinatal outcome of breech deliveries was 322 (83.9%). Adverse perinatal outcome of singleton term breech delivery was significantly associated with women's age of greater than or equal to 35 years (AOR = 2.62, 95% CI = 1.14–6.03), fully dilated cervix (AOR = 0.48, 95% CI = 0.25–0.91), ruptured membrane (AOR = 5.11, 95% CI = 2.25–11.6), and fetal weight of <2500 g (AOR = 6.77, 95% CI = 3.22–14.25). Conclusion Entrapment of head, birth asphyxia, and cord prolapse were the most common causes of perinatal mortality. Factors like fetal weight <2500 gm, mothers of age 35 years and above, those mothers not having a fully dilated cervix, and mothers with ruptured membrane were associated with increased perinatal mortality.
This scientific review of mode of transmission of COVID-19 is to aid scientific community in generating hypothesis. The inadequate evidence on SARS-CoV-2 transmission has hindered the development of effective prevention strategy and resulted in continues pandemic of the COVID-19. Therefore, in this review, existing evidence is discussed, hypothesis is generated regarding COVID-19 mode of transmission, and recommendations are forwarded based on existing body of knowledge. Thus, two meters (2 m) physical distance is not completely safe even for large droplets and wearing a face mask is a key in the prevention of SARS-CoV-2 in public areas and confined space and public need to be vaccinated.
Introduction: Since 1974, diclofenac has been used to treat the pain and swelling associated with rheumatic illnesses as a non-steroid anti-inflammatory medication (NSAID). It is one among the world's most extensively used non-steroidal anti-inflammatory medications (NSAIDs). Non-steroidal anti-inflammatory medicines have been shown to cause embryotoxicity and teratogenicity in experimental animals in a few studies, however there is no strong evidence of this impact in people.The aim of this study was to conduct a systematic assessment of the effects of diclofenac exposure on the mother and fetus during pregnancy.Methods: This study included all experimental, quasi-experimental, and observational research that were published in the English language and published up to the date of the review. PROSPERO (The International Prospective Register of Systematic Reviews) ID = CRD42019135608 was used to register the protocol. This study employed a three-step search technique. PubMed, Medline, SCOPUS, Web of Science, Embase, cinihal, Google, several university repositories, and Google scholar were among the databases searched. The titles and abstracts were then examined by two independent reviewers to see if they met the review's inclusion criteria. At the study level, two independent reviewers critically assessed eligible studies. The review's methodological quality was assessed at the result level using standardized critical assessment instruments from the Joanna Briggs Institute (JBI) for observational studies. Specific details about the demographics, study procedures, interventions, and outcomes of significance to the review purpose are included in the data retrieved from the studies. Due to the conclusion and type of the data, statistical pooling was not viable. As a result, the results were presented in a narrative format.Results: A total of 1,490,679 participants were found in three relevant papers (two cohorts and nested case-control studies). Diclofenac exposure during pregnancy raises the chance of low birth weight in the fetus, as well as the risk of spontaneous abortion and vaginal bleeding in the mother.Conclusions: Diclofenac exposure during pregnancy has negative consequences on the fetus and the mother. As a result, taking Diclofenac during pregnancy may have negative consequences for both the mother and the fetus, and more primary Randomized Control Trials (RCTs) are needed.
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