Outcomes and complications are reported as per the Reporting Standards for Endovascular Treatment of Pulmonary Embolism. Results: CDT was technically successful in 100% (n¼45) of patients. Main pulmonary artery pressure significantly decreased from 49.8 mm to 31.1 mm (po0.0001). Right ventricle dysfunction significantly improved with mean RV/ LV ratios decreasing from 1.59 to 0.93 (po0.0001). There were 6 complications: 4 minor bleeding episodes at access sites, and 2 major bleeding complications (flank and arm hematoma). All cause mortality at 30 days was 0%. There were no re-admissions for PE at 30 days after discharge in all patients. Conclusion: CDT is a safe and efficacious method in the treatment of SPE to reduce acute pulmonary hypertension and RVD. Using a standardized protocol for pulmonary thrombolysis may allow for more widespread adoption of interventional therapy.
Rationale and Objectives: Cystic lung disease may be accurately diagnosed by imaging interpretation of specialist radiologists, without other information. We hypothesized that with minimal training non-specialists could perform similarly to specialist physicians in the diagnosis of cystic lung disease. Methods: 72 cystic lung disease cases and 25 cystic lung disease mimics were obtained from three sources: 1) a prospective acquired diffuse lung disease registry, 2) a retrospective search of medical records and 3) teaching files. Cases were anonymized, randomized and interpreted by 7 diffuse lung disease specialists and 15 non-specialist radiologists and pulmonologists. Clinical information other than age and sex was not provided. Prior to interpretation, non-specialists viewed a short PDF training document explaining cystic lung disease interpretation. Results: Correct first choice diagnosis of 85% -88% may be achieved by high-performing specialist readers and 71% -80% by non-specialists and lower-performing specialists, with mean accuracies in the diagnosis of LAM (91%, p < 0.0001), BHD (93%, p < 0.0001), PLCH (89%, p < 0.0001) and LIP (92%, p < 0.0001). A strategy based on cyst appearance: simple cysts (LAM), peri-septal cysts (BHD), bizarre-shaped cysts (PLCH) and vascular indented cysts (LIP) gave non-specialists accuracies of 90% (p < 0.0001), 94% (p < 0.0001
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.