Generalised pustular psoriasis (GPP) is a rare, heterogeneous, chronic and potentially life-threatening autoinflammatory skin disease, characterised by episodes of widespread eruption of sterile, macroscopic pustules that occur with or without symptoms and signs of systemic inflammation. 1,2 The aberrant activation of the interleukin-36 pathway in patients with GPP causes an inflammatory reaction and widespread eruption of pustules. Flares, the acute phase of GPP involving widespread pustules, skin lesions and erythema, 3 typically last 2-5 weeks, 4 but may persist longer than 3 months and may be accompanied by systemic symptoms such as fever, pain, and fatigue. [5][6][7] While the most dominant cutaneous symptoms are pustules, erythema and scaling,
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