Sarangbanua traditional medicinal plant is found in Simalungunand NorthTapanuli Regencies, Sumatera, Indonesia. The result of plant determination, sarangbanuais Clerodendrumfragrans Vent Willd, including the Verbenaceae family. This study aims to determine the toxicity of the three types of leaf extracts of C. fragrans Vent Will. The Brine Shrimp Lethality Test (BSLT) method was used to determine the toxicity of the extracts. The mortality data were then analyzed by Probit SAS to obtain LC50 values. The results showed that the three types of C. fragrans leaf extracts had LC50 values below 1000 µg/mL, so they were classified as toxic and potentially bioactive. The LC50 values of each of the ethanol, ethyl acetate and ethanol extracts were 26.25; 37.50 and 41.97 µg/mL

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A new pyrone derivative, malakavalactone (2), was isolated from the acetone extract of Alpinia malaccensis fruits, along with a known compound kavalactone (1). The structure of the new compound was determined based on NMR and mass spectral data. Compounds 1 and 2 showed weak antibacterial activities against eight pathogenic bacteria.

This study aimed to perform a phytochemical screening and test the antibacterial, antioxidant, and anticancer activities of acetone extracts of the Coffee parasite (Loranthus ferrugineus Roxb). A phytochemical screen was performed using specific reagents. Antimicrobial testing was performed using the paper disc diffusion method. The antioxidant activity test used the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Anticancer activity test against HeLa and A549 cells based on the 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) assay method. Acetone extract L. ferrugineus Roxb contains alkaloids, flavonoids, triterpenoids, and tannins compounds. The acetone extract of L. ferrugineus Roxb showed activity against all the bacteria tested, with the inhibition zone diameter ranging from 6.2 mm - 11.1 mm. Acetone extract of L. Ferrugineus Roxb had a very strong antioxidant activity with a value of IC50 = 48.7122 µg/mL. The anticancer activity test showed cytotoxic activity against HeLa cells with a value of IC50 = 47.62 µg/mL and for A549 cells with a value of IC50 = 192.83 µg/mL.