ObjectivesThe purpose of this study was to validate a patch-based image denoising method for ultra-low-dose CT images. Neural network with convolutional auto-encoder and pairs of standard-dose CT and ultra-low-dose CT image patches were used for image denoising. The performance of the proposed method was measured by using a chest phantom.Materials and methodsStandard-dose and ultra-low-dose CT images of the chest phantom were acquired. The tube currents for standard-dose and ultra-low-dose CT were 300 and 10 mA, respectively. Ultra-low-dose CT images were denoised with our proposed method using neural network, large-scale nonlocal mean, and block-matching and 3D filtering. Five radiologists and three technologists assessed the denoised ultra-low-dose CT images visually and recorded their subjective impressions of streak artifacts, noise other than streak artifacts, visualization of pulmonary vessels, and overall image quality.ResultsFor the streak artifacts, noise other than streak artifacts, and visualization of pulmonary vessels, the results of our proposed method were statistically better than those of block-matching and 3D filtering (p-values < 0.05). On the other hand, the difference in the overall image quality between our proposed method and block-matching and 3D filtering was not statistically significant (p-value = 0.07272). The p-values obtained between our proposed method and large-scale nonlocal mean were all less than 0.05.ConclusionNeural network with convolutional auto-encoder could be trained using pairs of standard-dose and ultra-low-dose CT image patches. According to the visual assessment by radiologists and technologists, the performance of our proposed method was superior to that of large-scale nonlocal mean and block-matching and 3D filtering.

The role of the Brazilian Plateau (BP) in maintaining the South Atlantic convergence zone (SACZ) has been examined by statistical analysis and numerical experiments. Statistical analysis using 27 years of data showed that the SACZ is most intense when it is over the BP. In this case, low-level cyclonic circulation appears over the southwestern part of the BP and forms westerly flow, which intensifies low-level convergence along the SACZ with northeasterly flow from the Amazon and northerly flow along the western edge of the South Atlantic subtropical high. A vorticity budget analysis indicates that precipitation over the BP that accompanies stretching maintains the cyclonic circulation.Sensitivity experiments using a regional atmospheric model for two different cases indicate that precipitation over the BP plays a dominant role as an atmospheric heat source in maintaining the cyclonic circulation and the SACZ. In model experiments in which rain was stopped around the BP but the topography was kept, the cyclonic circulation disappeared, and the SACZ shifted southward away from its original position. In comparison with a control run, precipitation over the BP was weakened and the SACZ shifted southward in experiments in which the BP was removed or its complex, multiple-valley terrain was smoothed out. The results of this study support the ideas suggested in previous studies (i.e., that the BP has an anchor effect on the SACZ): Precipitation is intensified over the complex terrain of the BP, and mechanisms of conditional instability of the second kind occur between the precipitation over the BP and the cyclonic circulation to its southwest, which intensifies moisture convergence over the plateau. * Current affiliation: Seiai Junior and Senior High School, Hirosaki, Aomori, Japan.