In recent decades, there has been a great deal of interest in conducting polymers due to their broad applications. At the same time, various synthetic techniques have been developed to produce various nanostructures of the conducting polymers with their fascinating properties. However, the techniques for the manufacture of 2D nanosheets are either complex or expensive. No comprehensive approach for constructing 2D and 3D materials or their composites has been documented. Herein, a simple and scalable synthetic protocol is reported for the design of 2D, 3D, and related conducting polymer nanocomposites by interface manipulation in a bicontinuous microemulsion system. In this method, diverse bicontinuous thin layers of oil and water are employed to produce 2D nanosheets of conducting polymers. For the fabrication of 3D polypyrrole (PPY) and their composites, specially designed linkers of the monomers are applied to lock the 3D networks of the conducting polymers and their composites. The technique can be extended to the fabrication of most conducting polymer composites, being cost‐effective and easily scalable. The optimum electrical conductivity obtained for 2D PPY nanosheets is 219 S cm−1, the highest literature value reported to date to the best of knowledge.

This article presents a comprehensive review of current Magnetic Imaging Techniques (MIT), specifically Magnetic Particle Imaging (MPI) and Magnetic Resonance Imaging (MRI) methods as well as their impacts and potential in biomedical applications.The paper particularly focuses on several perspectives of MPI and MRI techniques including technical considerations, advantages, limitations, applications, future trends. Surprisingly, there are not many review articles that focused on MPI and MRI. This review will give a complete overview of present technology, perspectives, and potential future developments for MPI and MRI. MIT has become an essential and integral part of medical diagnosis in many large medical clinics and hospitals. This area is rapidly developing and evolving to meet the huge demands in medical diagnosis and prevention. MPI and MRI are promising technologies that provide reliable and effective diagnosis for many diseases including cancer. MIT uses non-invasive scanning to obtain a detailed image of the body's tissues or organs without the necessity for surgery. These techniques allow us to detect symptoms of serious diseases at an early stage. Early detection also gives patients the chance to get the right care before their illnesses advance to a late, incurable stage, potentially saving many lives.

In this work, Sulfur and Nitrogen co-doped carbon nanoparticles (SN-CNPs) were synthesized by hydrothermal method using dried beet powder as the carbon source. TEM and AFM images indicated that these SN-CNPs form a round-shape ball with an approximate diameter of 50 nm. The presence of Sulfur and Nitrogen in these carbon-based nanoparticles was confirmed by FTIR and XPS analyses. These SN-CNPs were found to have strong phosphatase-like enzymatic activity. The enzymatic behavior of SN-CNPs follows the Michaelis–Menten mechanism with greater vmax and much lower Km values compared to alkaline phosphatase. Their antimicrobial properties were tested on E. coli and L. lactis, with MIC values of 63 μg mL−1 and 250 μg mL−1, respectively. SEM and AFM images of fixed and live E. coli cells revealed that SN-CNPs strongly interacted with the outer membranes of bacterial cells, significantly increasing the cell surface roughness. The chemical interaction between SN-CNPs and phospholipid modeled using quantum mechanical calculations further support our hypothesis that the phosphatase and antimicrobial properties of SN-CNPs are due to the thiol group on the SN-CNPs, which is a mimic of the cysteine-based protein phosphatase. The present work is the first to report carbon-based nanoparticles with strong phosphatase activity and propose a phosphatase natured antimicrobial mechanism. This novel class of carbon nanozymes has the potential to be used for effective catalytic and antibacterial applications. Graphical abstract

In this work, Sulfur and Nitrogen co–doped carbon nanoparticles (SN–CNPs) were synthesized by hydrothermal method using the dried beet powder as the carbon source. TEM and AFM images indicated that these SN–CNPs form a round-shape ball with an approximate diameter of 50 nm. The presence of Sulfur and Nitrogen in these carbon-based nanoparticles was confirmed by FTIR and XPS analyses. These SN–CNPs were found to have strong phosphatase–like enzymatic activity. The enzymatic behavior of SN–CNPs follows the Michaelis–Menten mechanism with greater vmax and much lower Km values compared to alkaline phosphatase. Their antimicrobial properties were tested on E. coli and L. lactis, and values of MIC were identified as 47-µg mL–1 and 188-µg mL–1, respectively. SEM and AFM images of fixed and live E. coli cells showed that SN–CNPs strongly interacted with the outer membranes of bacterial cells, which greatly increased the cell surface roughness. The chemical interaction between SN–CNPs and phospholipid modeled using quantum mechanical calculations further support our hypothesis that the phosphatase and antimicrobial properties of SN–CNPs are due to the thiol group on the SN–CNPs, which is a mimic of the cysteine–based protein phosphatase. The present work is the first to report carbon–based nanoparticles with phosphatase activity and propose a phosphatase natured antimicrobial mechanism. This novel class of carbon nanozymes has the potential to be used for effective catalytic and antibacterial applications.

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