INTRODUCTION: Sensitive Skin Syndrome (SSS) is officially defined as a syndrome with unpleasant sensations like itching, pain, and numbness in response to stimuli that usually do not cause such sensations. In most of the cases it is a self-defined condition without objective pathological findings. Few studies have underlined the influence of SSS on the quality of life (QoL). The main problem is that people with sensitive skin suffer both with and without topical or internal care, which puts them in an extremely complex position and still without a solution. AIM: The aim of the study was to assess the impact of SSS on QoL. MATERIALS AND METHODS: The presented study includes 304 females self-diagnosed with SSS. Demographic data and disease-related characteristics were collected. The measurement tools, for assessing Sensitive Skin included 10-item version of Sensitive Scale. For the evaluation of QoL Dermatological Life Quality Index (DLQI) a questionnaire was applied. Additionally, QoL of these patients was comparable to that of patients with hand eczema (HE) and those suffering from dermatoses accompanied by severe itch (Lichen simplex chronicus LSC). RESULTS AND DISCUSSION: Results showed the overall frequency of SSS-31.97% with the following distribution 57.23% in aesthetic visitors and 42.77% in those with a health problem. The total DLQI score reported by the SSS-patients was 8.4±3.29. Patients scores were significantly high for Q1 (feelings), Q2 (embarrassment), and Q3 (free time/leisure) (p<0=001). CONCLUSION: All the reported and analyzed results indicate that SSS has a negative impact on most of the QoL-domains for every patient (p<0.001). Consequently, sensitivity of skin moderately affects QoL of the patients. This is the first study in our country, which aims to measure the impact of sensitive skin on QoL of patients.

Carcinoma erysipeloides (CE) is an uncommon cutaneous metastasis of advanced breast carcinoma, showing distinctive features and presenting as a well-demarcated erythematous macule or plaque varying in size. It also may show a raised border and oedema. The differential diagnoses include erysipelas or cellulitis of the breast, or rarely-radiodermatitis. Most of the time CE is associated with advanced breast cancer and rarely with neoplastic tumours of the colon, pancreas, oesophagus, uterus, etc. We report a 58-year-old woman who presented at the Medical Institute of the Ministry of Internal Affairs with a 1-month history of not well-demarcated, erythematous, oedematous patches and plaques on the left and right breast, abdomen and both shins, associated with advanced invasive lobular carcinoma of the breast.

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INTRODUCTION: Erysipelas is a common, ubiquitous bacterial infection of the skin mainly caused by Streptococcus pyogenes-group A beta-hemolytic streptococcus. The current epidemiology of the disease demonstrates an upward trend in cases with primary and recurrent erysipelas, a change in the site of predilection-from face to lower limbs, and an increase of severe cases with a hemorrhagic or bulloushemorrhagic component. To date, the alterations in hemostasis due to streptococcal bacterial infection are still not well defined. Despite the advanced treatment of erysipelas, in approximately 10% of patients with hemorrhagic and bullous-hemorrhagic erysipelas, a skin necrosis has occurred. The combination of severe types of erysipelas with local and general predisposing factors such as diabetes mellitus, obesity, chronic vessel insufficiency results in recurrences and complications with high percentage of disability. In addition, streptococcal infections may have fulminant progression as for every 1 hour delay of adequate treatment, the percent of mortality increases with 7.5%. AIM: The purpose of this paper is to establish the current concepts and observations of hemostatic changes in erysipelas. MATERIALS AND METHODS: Literature referred in MEDLINE, Web of Science, Scopus has been studied. RESULTS: The hemostasis changes in erysipelas are not well researched. The available literature is insufficient as the studies are based on a small number of patients, which prevents any significant conclusions. CONCLUSION: The increasing incidence of patients with severe form of erysipelas stresses the need to intensify the study of hemostasis in erysipelas. Knowing the mechanisms of coagulation changes might help to predict and prevent severe, irreversible complications.