Aim: Fibromyalgia syndrome is a common musculoskeletal disorder, characterized by chronic widespread pain, multiple tender points, joint stiffness, and systemic symptoms without any underlying organic disease. The initial aim of the present study was to determine the vitamin D levels in patients with fibromyalgia and compare these values to those found in healthy subjects. Then, correlations between functional status, clinical severity of the disease, and vitamin D levels were assessed. Material and Methods: This case-control study included 137 female fibromyalgia patients and 109 healthy female counterparts. The severity of pain was assessed by a visual analogue scale and the functional impact was evaluated through the Fibromyalgia Impact Questionnaire in the patient group. Vitamin D levels were compared between groups, and the correlation between vitamin D levels and questionnaire scores was determined. Results: Vitamin D and parathormone levels did not differ significantly between groups (p=0.858, p=0.790 respectively). The mean Fibromyalgia Impact Questionnaire scores and the medians for the visual analogue scale did not differ significantly among vitamin D deficient, insufficient, and sufficient patients (p=0.548 , p=0.952 respectively). In addition, no significant correlation between vitamin D levels and the Fibromyalgia Impact Questionnaire score was found(Spearman’s rho=0.056, p=0.513). Conclusion: This study did not show any significant differences between the vitamin D levels of fibromyalgia patients and those of healthy subjects. Further, in fibromyalgia patients, there was no correlation between vitamin D levels and functional status or disease severity
ObjectivesTherapeutic ultrasound (TUS) is one of the most commonly used modalities in low back pain treatment. The objective of this study was to determine whether TUS applied to the low back region in patients with chronic low back pain had any effect on renal function.MethodsForty patients with chronic low back pain were randomized to 2 groups by a block randomization method. Thirty‐seven patients completed the final evaluation. All patients were treated for 5 sessions per week for 3 weeks with the same physiotherapy modalities (superficial heating and transcutaneous electrical nerve stimulation) and exercise therapy; in addition to these treatments, the second group was treated with TUS for 10 minutes (frequency, 1 MHz; intensity, 1.5 W/cm2; and effective irradiation area of the transducer head, 5 cm2). The serum creatinine, serum cystatin C, 24‐hour urine creatinine, creatinine clearance, 24‐hour urine microalbumin and microprotein, urine volume, and glomerular filtration rate were measured. The patients were evaluated at baseline (day 0) and the end of the treatment (day 21).ResultsThe serum cystatin C levels were increased in both groups, but this increase was not significant (P > .05). There was no difference between the groups in the percent change in all outcome measures (P > .05).ConclusionsThis showed that TUS applied to the low back region does not affect renal function.
Amaç: Kronik bel ağrılı hastalarda uyku kalitesini değerlendirmek ve uyku kalitesi ile ağrı, fonksiyonel durum ve yaşam kalitesi arasındaki ilişkiyi incelemek, ayrıca kronik bel ağrısı ile depresyon durumu arasındaki ilişkiyi ortaya koymaktır. Gereç ve Yöntemler: Çalışmaya kronik bel ağrılı 100 hasta ve 100 kas-iskelet ağrısı olmayan birey alındı.Bel ağrısı düzeyi Vizüel Analog Skala (VAS), fonksiyonel durum Roland Morris Özürlülük Ölçeği, uyku kalitesi Pittsburg Uyku Kalitesi Ölçeği (PUKI), sağlıkla ilişkili yaşam kalitesi Kısa Form -36(KF-36) ve depresyon durumu Beck Depresyon Ölçeği ile değerlendirildi. Bu değerlendirme ölçekleri ile gruplar karşılaştırılmıştır. Ayrıca uyku kalitesi ile ağrı şiddeti, fonksiyonel durum, yaşam kalitesi ve depresyon durumu arasındaki ilişki incelenmiştir. Bulgular: Kronik bel ağrılı hastaların PUKI skoru kontrol grubundan anlamlı olarak daha yüksekti. [PUKI ortancası hasta grubu 5 (1-14), kontrol grubu 4 (0-15), p=0.014].Uyku kalitesi ile VAS-gece arasında istatistiksel anlamlı ilişki saptandı (p=0.005). Hasta grubunda KF-36’nın fiziksel fonksiyon, fiziksel rol güçlüğü, canlılık, sosyal işlevsellik, ağrı ve genel sağlık algısı alt parametrelerinde kontrol grubuna göre istatistiksel anlamlı düşük puan saptandı (Sırasıyla p
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