To date, a large number of case reports have emerged claiming COVID-19 reinfection, some confirmed by the distinct viral genotypes in each episode. [1][2][3][4][5][6][7][8][9] This communication highlights a case report from Delhi, India, with two instances of SARS-CoV-2 where the second episode witness moderate illness after 73 days of the first SARS-CoV-2 positive episode (asymptomatic). A 52-year-old male individual was tested positive at a COVID health care unit [RT-PCR/ Ct-values (ORF1ab-36.04/E gene-36.74)-using Roche Cobas 6800] for SARS-COV-2 on June 12, 2020, upon contact tracing. At that AUTHOR CONTRIBUTIONS
Crimean Congo Hemorrhagic fever (CCHF), Kayasanur Forest Disease (KFD), and Scrub Typhus (ST) are re-emerging Vector-borne zoonotic Diseases (VBZD) in different parts of the world including India. Still, factors associated with the epidemiological components, agents, hosts and environment of these diseases are needed to probe to intersect them to break the cycle of disease transmission. National One Health program is the most appropriate to prevent and control Zoonotic diseases as it involves multisectoral collaboration. The present article is made to propose novel strategies for a nationwide campaign. It is based on gaps identified in existing
Rabies is a fatal zoonotic disease which has tormented humanity since antiquity. It is transmitted after the bite of a rabid animal and is 100 % fatal if timely intervention of appropriate wound management and Anti Rabies Prophylaxis is not given to the animal bite victims. About 96% of the mortality and morbidity is associated with dog bites.
Orientia tsutsugamushi is a mite-borne bacterium belonging to the family Rickettsiaceae and is responsible for a disease called scrub typhus in humans, which is transmitted by the vector mite Leptotrombidium deliense (common ectoparasite on rodents) in most of Asian countries including India. The study conducted in selected villages of Karnal and Kaithal districts of Haryana state, India revealed four species of rodents - Rattus rattus, norveigicus, Bandicota indica and Suncus murinus. Dust mite Dermatophagoides farina; chigger mite L. deliense and fleas Xenopsylla astia and X. cheopis were prevalent on the rodents.
Rabies is a global problem and is endemic in India. Rabies cases occur throughout the year, and the majority of cases are associated with dog bites. We report a rabies outbreak investigation in an urban area of Delhi conducted by our multidisciplinary team, and its role in proactively controlling a rabies outbreak by concerted efforts and timely advice to various stakeholders using a “One Health Approach.” A veterinary care NGO from Delhi picked up a suspected rabid stray dog and submitted a brain sample for diagnosis of rabies, as they had received information from a resident of the locality about an unprovoked animal bite incident involving a girl (category III bite) and close contact of two more stray dogs living in the vicinity of the suspected rabid dog. The laboratory diagnosis of rabies in the suspected dog brain sample was confirmed by using Fluorescence Antibody Test (FAT). A multi-expert investigation team with expertise in medicine, microbiology, veterinary sciences, laboratory diagnosis, and public health was constituted to investigate the outbreak. The timely, adequate, and appropriate anti-rabies management initiated for the animal bite victims in this incident could prevent rabies. Proactive involvement of multiple stakeholders and knowledge attributes and practice of local residents could prevent human rabies. As there were no further reports of dog bites from the area, the chain of rabies transmission in that area could be controlled. The presented work is a classical case scenario where concerted efforts of all stakeholders achieved effective control and prevention of rabies by adopting the “One Health approach”.
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