Little is known about the timing and the vegetation dynamics shortly after the Last Glacial Maximum (LGM) on the Swiss Plateau 19,000−15,000 cal B.P. Subsequent Late Glacial and Holocene vegetation changes are better known; however, it is unclear if the few available palynological and macrofossil records are able to capture the entire vegetation variability of the region. A new palaeoecological multiproxy study using pollen, spores, charcoal and X-ray fluorescence (XRF) from Burgäschisee (Swiss Plateau, 465 m a.s.l.) is used to reconstruct vegetation, fire and land use for the past 19,000 cal. years. Steppe tundra vegetation established at c. 18,700 cal B.P. only c. 300 years after the end of the LGM and deglaciation. A shift from steppe tundra (Artemisia, Helianthemum) to shrub tundra (Betula nana, Salix, Juniperus) with sporadic tree Betula stands occurred around 16,000 cal B.P., most likely in response to climate warming after the end of Heinrich event 1. Abundant spores of coprophilous fungi (Sporormiella, Cercophora) may reflect the presence of Pleistocene large herbivores (e.g. Mammuthus primigenius, Bison bonasus, Rangifer tarandus). Afforestation started more than 2,000 years later with Juniperus and tree Betula around 14,500 cal B.P. Mixed Betula and Pinus sylvestris forests persisted until the onset of the Holocene at 10,800 cal B.P., when mixed elm forests expanded into the region in response to climate warming. Around 8,200 cal B.P., mesophilous Fagus sylvatica and Abies alba partly replaced more heliophilous species in the forests, when climate became less continental and more moist. Pollen of Cerealia, Plantago lanceolata and other crops and weeds suggest that agricultural activities became significant during the Neolithic around 6,500 cal B.P. (4,550 cal B.C.). Archaeological findings from Neolithic pile dwellings around 5,950 cal B.P. (4,000 cal B.C.) indicate local settlements around the lake. The lake sediments are laminated for most of the last c. 6,800 years. With two independent proxies (XRF and pollen), we can demonstrate that these laminations are annual, suggesting short-term mixing of the lake water due to a more open landscape in response to land use. Our study shows that the annually laminated (varved) sediments from Burgäschisee have a great potential for high resolution multi-proxy analyses covering the past c. 6,800 years. They can provide accurate ages of cultural phases that might be compared with dendro-chronologically dated evidence from lake dwellings.