The aim of this study was to determine population parameters of Squalius cappadocicus in Melendiz River. A total of 357 specimens, collected 2016 June-2017August. Age of the specimens ranged from 0th to 5th age groups and dominant age group was found I (30,53%) followed by 0th (%28,29) and 2nd (%20,44) age groups. Total length varied from 2.6-24.5 cm with the mean of 11.27±3.88 cm, total weight ranged from 0.44 to 202.99 with the mean of 23.57±25.32 g. Length-weight relationship were estimated W=0.0120*L2.9882. Estimated population parameters were calculated as L∞: 44.21 cm, k: 0.098, to: -1.47, Φꞌ: 2.28 and K: 1.13 for the population. Mortality and exploitation rates estimated as Z: 0.37, M: 0.32, F: 0.05 and E: 0.13, respectively. These values suggested that there is no over fishing pressure on the population.