Further information on research design is available in the Life Sciences Reporting Summary linked to this article. Data availability The LifeLines-DEEP metagenomics sequencing data are available at the European Genome-phenome Archive (EGA), with access code EGAS00001001704. Genotype and phenotype data can be requested from the Lifelines Biobank https://www.lifelines.nl/ researcher/biobank-lifelines/application-process. Summary statistics for metabolic traits were downloaded from MAGIC, GIANT and DIAGRAM websites (see URLs).
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.